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Estradiol
go.drugbank.com/drugs/DB00783ApprovedInvestigationalVet approved[DB00977] (EE) is a synthetic form of estradiol commonly used as the estrogenic component of most combination oral contraceptive pills (OCPs). … Because it has a low oral bioavailability on its own, estradiol is commonly formulated with an ester side-chain.
Mixtures: Angeliq 1 mg/2 mg Filmtabletten, Parapanol kombi 2 mg/1 mg - FilmtablettenCategories: Sex Hormones and Modulators of the Genital SystemLevodopa
go.drugbank.com/drugs/DB01235ApprovedInvestigationalOnce past the blood-brain barrier, levodopa is metabolized to dopamine and supplements the low endogenous levels of dopamine to treat symptoms of Parkinson's[Label]. … Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally administered with a dopa decarboxylase inhibitor like carbidopa to prevent metabolism until after
Mixtures: LEVOCAENT OR 100/25/200, LEVOCAENT OR 100/25/200Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromePyridoxine
go.drugbank.com/drugs/DB00165ApprovedInvestigationalNutraceuticalVet approvedPyridoxine is used medically for the treatment of vitamin B6 deficiency and for the prophylaxis of isoniazid-induced peripheral neuropathy (due to [DB00951]'s mechanism of action which competitively inhibits … the action of pyridoxine in the above-mentioned metabolic functions).
Mixtures: Sun-rype Vitaburst, Multi-Nate 30Categories: Drugs for Treatment of TuberculosisSipuleucel-T
go.drugbank.com/drugs/DB06688ApprovedInvestigationalThe treatment initially cost $93,000 at the time of FDA approval, but rose to over $100,000 in 2014. … Food and Drug Administration (FDA) on April 29, 2010, to treat asymptomatic or minimally symptomatic metastatic Hormone-Refractory Prostate Cancer (HRPC).
Vecabrutinib
go.drugbank.com/drugs/DB16657InvestigationalVecabrutinib is under investigation in clinical trial NCT03037645 (Safety, PK, PD, and Antitumor Activity of Vecabrutinib (SNS-062) in B Lymphoid Cancers).
SF1126
go.drugbank.com/drugs/DB05210InvestigationalSF1126 is an integrin-targeted PI3 kinase inhibitor.
Ulipristal
go.drugbank.com/drugs/DB08867ApprovedInvestigationalA recent systematic review proclaimed that the majority of available evidence demonstrates an inhibitory effect on ovulation rather than a post-fertilization effect on the endometrium, which has been heavily … Ulipristal is a selective progesterone receptor modulator used for the purposes of emergency contraception (Ella) and for the treatment of uterine fibroids (Fibristal).
Categories: Sex Hormones and Modulators of the Genital SystemProducts: Femke 30 mg Filmtablette, Diapill 30 mg FilmtablettenPropylene glycol
go.drugbank.com/drugs/DB01839ApprovedInvestigationalA clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
Mixtures: Dg Lubricant Eye Drops, DG Lubricant Eye DropsCategories: Compounds used in a research, industrial, or household settingCandesartan cilexetil
go.drugbank.com/drugs/DB00796ApprovedInvestigationalUnlike angiotensin-converting enzyme (ACE) inhibitors, ARBs do not have the adverse effect of dry cough. … Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension.
Mixtures: UNISIA 8 MG/5 MG, UNISIA 8 MG/5 MGCategories: Agents Acting on the Renin-Angiotensin SystemBisphosphocin Nu-3
go.drugbank.com/drugs/DB16015InvestigationalBisphosphocin Nu-3 is under investigation in clinical trial NCT02737722 (Topically Applied Bisphosphocin Nu-3 on Infected Diabetic Ulcers of Subjects With Type I or II Diabetes Mellitus).
Synonyms: Nu-3, Bisphosphocin Nu-3