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Valaciclovir
go.drugbank.com/drugs/DB00577ApprovedInvestigationalValaciclovir (valacyclovir), also known as _Valtrex_, is an antiviral drug that has been used to manage and treat various herpes infections for more than 2 decades. … It was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline [L5671]. Valacyclovir is the L-valine ester of aciclovir.
Categories: Heterocyclic Compounds, 2-RingSynonyms: L-Valine, 2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)ethyl ester, L-Valine ester with 9-((2-hydroxyethoxy)methyl)guanineRituximab
go.drugbank.com/drugs/DB00073ApprovedInvestigationalOn November 28, 2018, the US FDA approved _Truxima_, the first biosimilar to Rituxan (Rituximab) [L4808]. … It was originally approved by the U.S.
Categories: CD20 (Clusters of Differentiation 20) inhibitorsProducts: NOVEX 100 MG/10 ML I.V. İNFÜZYONLUK ÇÖZELTİ İÇİN KONSANTRE, 2 FLAKON, MABTHERA 100 MG/10 ML IV INFUZYON İÇİN KONSANTRE ÇÖZELTİ İÇEREN FLAKON, 2 ADETTolvaptan
go.drugbank.com/drugs/DB06212ApprovedInvestigationalFDA approved on May 19, 2009.
Categories: Heterocyclic Compounds, 2-RingProducts: SAMSCA 30 MG TABLET, 10 ADET, SAMSCA 15 MG TABLET, 10 ADETCandesartan cilexetil
go.drugbank.com/drugs/DB00796ApprovedInvestigationalCandesartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone system (RAAS); it competes with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and prevents … It may also be used as an alternative agent for the treatment of heart failure, systolic dysfunction, myocardial infarction and coronary artery disease.
Mixtures: TANSİFA 16 MG/10 MG TABLET, 28 ADET, CANLOX 16 MG/10 MG TABLET, 28 TABLETCategories: Heterocyclic Compounds, 1-Ring, Angiotensin 2 Receptor BlockerPyrantel
go.drugbank.com/drugs/DB11156ApprovedVet approvedPyrantel is mainly available in formulations for dogs and cats as the embonate salt, containing a 34.7% pyrantel base [L1900]. … Pyrantel has shown to be effective after a single dose [L1905]. In humans, it is administered as pyrantel pamoate [A32282],[A32283],[L1893],[L1898].
Mixtures: PAMOXPEN - PAMOATO DE PIRANTEL100 MG+ PAMOATO DE OXANTEL 100 MG TABLETAS, PAMOATO DE OXANTEL 250 MG/5ML + PAMOATO DE PIRANTEL 250 MG/5 ML SUSPENSIÓN.Categories: Heterocyclic Compounds, 1-RingPemetrexed
go.drugbank.com/drugs/DB00642ApprovedInvestigationalIts use in non-small cell lung cancer has also been investigated. Pemetrexed was first approved by the FDA in February 4, 2004.[A253907]
Categories: Heterocyclic Compounds, 2-RingProducts: Pemetrexed Zentiva 10 mg/ml Infusionslösung, ALIMTA INFUZYON COZELTISI ICIN TOZ ICEREN FLAKON 10 ML, 1 ADETExenatide
go.drugbank.com/drugs/DB01276ApprovedInvestigationalExenatide was given FDA approval on April 28, 2005[L6106]. It is available as immediate- and extended-release formulations. … Exenatide is a glucagon-like peptide-1 (GLP-1) analog[L42690].
Categories: Glucagon-like peptide-1 (GLP-1) analogues, GLP-1 AgonistsProducts: BYETTA 10 µG/40 µL SC KULLANIMA HAZIR DOLU ENJEKSİYON KALEMI ICINDE COZELTI, 2.4 ML (60 DOZ), BYETTA 5 µG/20 µL SC KULLANIMA HAZIR DOLU ENJEKSİYON KALEMI ICINDE COZELTI, 1.2 ML (60 DOZ)Lomitapide
go.drugbank.com/drugs/DB08827Approved[A7367] Lomitapide was first approved by the FDA in December 2012 and the EMA in July 2013 as an adjunct to a low-fat diet and other lipid-lowering treatments.[A275444, A275446] … [A275444, A7367] It was developed to address the significant unmet medical need in patients with homozygous familial hypercholesterolemia (HoFH)—an ultra-rare and life-threatening genetic disorder characterized
Categories: Heterocyclic Compounds, 2-RingSynonyms: 9H-FLUORENE-9-CARBOXAMIDE, N-(2,2,2-TRIFLUOROETHYL)-9-(4-(4-(((4'-(TRIFLUOROMETHYL)(1,1'-BIPHENYL)-2-YL)CARBONYL)AMINO)-1-PIPERIDINYL)BUTYL)-, N-(2,2,2-TRIFLUOROETHYL)-9-(4-(4-(((4'-(TRIFLUOROMETHYL)BIPHENYL-2-YL)CARBONYL)AMINO)PIPERIDIN-1-YL)BUTYL)-9H-FLUORENE-9-CARBOXAMIDEIoversol
go.drugbank.com/drugs/DB09134ApprovedInvestigational[L41780] Iodine has a high atomic density, which gives it the ability to attenuate X-rays. … Ioversol is a non-ionic compound with a tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of organs and tissues.
Synonyms: N,N'-Bis (2,3-dihydroxypropyl)-5-[N-(2-hydroxyethyl) -glycolamido] -2,4,6-triiodoisophthalamideInternational brands: OPTIRAY 320Cladribine
go.drugbank.com/drugs/DB00242ApprovedInvestigational[A350] Cladribine was first approved in the United States in 1993 [A263713] initially as a treatment for a number of hematological malignancies; currently, it is approved for the treatment of hairy cell … [A263733] In 2017 in Europe and in 2019 in the United States, cladribine was also approved for the treatment multiple sclerosis.[A263718]
Categories: 2-Chloroadenosine, Heterocyclic Compounds, 2-RingSynonyms: 2-Chloro-2'-deoxyadenosine, 2-chloro-2′-deoxy-adenosine