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Isosorbide mononitrate
go.drugbank.com/drugs/DB01020ApprovedInvestigational[L11743] Isosorbide mononitrate has a longer duration of action than [nitroglycerin] due to its slow onset of absorption and metabolism. … Like other organic nitrates, isosorbide mononitrate acts as a prodrug for its active metabolite, [nitric oxide], which mediates the therapeutic action of isosorbide mononitrate.
Synonyms: IS 5-MN, IS-5-MNProducts: ISMN AL 100 RETARD, Monoket retard 50 mg - KapselnTestosterone cypionate
go.drugbank.com/drugs/DB13943ApprovedInvestigationalIt was developed by the company Pharmacia and Upjohn and FDA approved on July 25, 1979.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesProducts: DEPO-TESTOSTERONE STERILE SOLUTION 100 mg/ml, DEPO-TESTOSTERONE STERILE SOLUTION 200 mg/mlFluoxetine
go.drugbank.com/drugs/DB00472ApprovedInvestigationalVet approvedFluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI). … [A181673] It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies
Mixtures: Sentraflox AM-10, TARGET 6 MG /50 MG KAPSUL, 90 ADETCategories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2C Receptor AntagonistsSomatotropin
go.drugbank.com/drugs/DB00052ApprovedInvestigational[Somatrem] was the first available recombinant HGH and was largely replaced by somatropin, another form of recombinant HGH. … It has an identical primary protein structure to endogenous human growth hormone.[A228188] Recombinant HGH has been commercially available since 1985 after its development by Genentech.
Mixtures: Nutropin - Kit Pws(5mg) & Liq(10ml) Im ScCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersCitalopram
go.drugbank.com/drugs/DB00215ApprovedInvestigational[A261316] Citalopram was approved by the FDA in 1998 for the treatment of depression in adults 18 years or older.[L5230] … [A261316,A14720] Specifically, it has a very minimal effect on dopamine and norepinephrine transportation and virtually no affinity for muscarinic, histaminergic, or GABAergic receptors.
Mixtures: Sentralopram AM-10Categories: Serotonin 5-HT2 Receptor Antagonists, Cytochrome P-450 SubstratesPimozide
go.drugbank.com/drugs/DB01100ApprovedA diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol for the suppression of vocal and motor tics in patients with Tourette syndrome. … Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated. (From AMA Drug Evaluations Annual, 1994, p403)
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsProducts: NOROFREN 2 MG TABLET, 10 ADET, NOROFREN 2 MG TABLET, 500 ADETRasagiline
go.drugbank.com/drugs/DB01367ApprovedInvestigationalRasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: RASAsunaprevir
go.drugbank.com/drugs/DB11586ApprovedWithdrawnAsunaprevir, also named BMS-650032, is a potent hepatitis C virus (HCV) NS3 protease inhibitor. … [A32528] It was developed by Bristol-Myers Squibb Canada and approved by Health Canada on April 22, 2016. The commercialization of asunaprevir was cancelled one year later on October 16, 2017.[L1113]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesProducts: SUNVEPRA 100 MG KAPSÜL, 56 ADETCangrelor
go.drugbank.com/drugs/DB06441ApprovedInvestigationalCangrelor was approved by the FDA in June 2015 for intravenous application. … An advantage Cangrelor provides over oral P2Y12 inhibitors (such as prasugrel, ticagrelor, and clopidogrel) is that it is an active drug not requiring metabolic conversion therefore providing a rapid onset
Synonyms: [dichloro-[[[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(2-methylsulfanylethylamino)-2-(3,3,3-trifluoropropylsulfanyl)purin-9-yl]oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]methyl]phosphonic acidProducts: KENGREXAL 50 MG ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ, 10 ADETBenzoyl peroxide
go.drugbank.com/drugs/DB09096ApprovedInvestigational[A18903,A233859] This treatment decreases keratin and sebum around follicles, as well as increasing turnover of epithelial cells. … [L33249,L33264,L33269,L33299,L33314] It has been formulated as products with either a single active ingredient,[L33249,L33299] or with [erythromycin],[L33264] [clindamycin],[L33269] or [adapalene].
Mixtures: OXIMIN 10 MG/G + 50 MG/G JEL,50 G, OXIMIN 10 MG/G + 50 MG/G JEL,25 GProducts: TRİAKNE %10 EMÜLSİYON JEL, 50 G, Panoxyl 10 Bar 10%