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Displaying results 7151 - 7160 of 10000 in total
  1. Drug

    Icenticaftor

    go.drugbank.com/drugs/DB21466
    Investigational

    Icenticaftor is under investigation in clinical trial NCT04396366 (Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of QBW251 in Subjects With Bronchiectasis). … The usage of the INN stem '-caftor' in the name indicates that Icenticaftor is a Cystic fibrosis transmembrane regulator (CFTR) protein modulator, corrector, and amplifier.

  2. Drug

    Linvencorvir

    go.drugbank.com/drugs/DB21544
    Investigational

    Linvencorvir is a small molecule drug. The usage of the INN stem '-corvir' in the name indicates that Linvencorvir is a core protein (Cp) inhibitor. … Linvencorvir is under investigation in clinical trial NCT04225715 (A Trial To Evaluate The Efficacy And Safety Of Multiple Combination Therapies In Participants With Chronic Hepatitis B).

  3. Drug

    Fipravirimat

    go.drugbank.com/drugs/DB21578
    Investigational

    Fipravirimat is under investigation in clinical trial NCT04493216 (A Dose-Range Finding Clinical Trial Study in Human Immunodeficiency Virus (HIV-1) Infected Treatment-Naive Adults). … Fipravirimat is a small molecule drug. The usage of the INN stem '-virimat' in the name indicates that Fipravirimat is a antiviral, disruptor of viral maturation.

  4. Drug

    Foselutoclax

    go.drugbank.com/drugs/DB21663
    Investigational

    Foselutoclax is a small molecule drug. The usage of the INN stem '-toclax' in the name indicates that Foselutoclax is a B-cell lymphoma 2 (Bcl-2) inhibitor. … Foselutoclax is under investigation in clinical trial NCT06011798 (Assess the Efficacy and Safety of Repeat Intravitreal Injections of Foselutoclax (UBX1325) in Patients With DME (ASPIRE)).

  5. Drug

    MF-300

    go.drugbank.com/drugs/DB32060
    Investigational

    MF-300 is an investigational, first-in-class, small molecule inhibitor of 15-hydroxyprostaglandin dehydrogenase. … As a potential candidate for the treatment of sarcopenia, it has undergone phase 1 studies to evaluate safety, tolerability, and PK/PD characteristics.[A275368,L54983]

  6. Drug

    Elbimilast

    go.drugbank.com/drugs/DB20663
    Investigational

    Elbimilast is under investigation in clinical trial NCT00977886 (Safety and Pharmacokinetics of ELB353 in Healthy Men). Elbimilast has a monoisotopic molecular weight of 442.04 Da. … Elbimilast is a small molecule drug. The usage of the INN stem '-milast' in the name indicates that Elbimilast is a Phosphodiesterase-4 (PDE4) inhibitor.

  7. Drug

    Cimetropium

    go.drugbank.com/drugs/DB09271
    Investigational

    It is also endowed of a direct myolitic action which partially accounts for its antispasmodic activity. It has never been approved for use in the U.S. or Canada. … Cimetropium is a semi-synthetic belladonna alkaloid and derivative of scopolamine. It is a potent antimuscarinic and an effective antispasmodic drug.

    Synonyms: Cimetropium ion
  8. Drug

    Cimlanod

    go.drugbank.com/drugs/DB14983
    Investigational

    Cimlanod is under investigation in clinical trial NCT02819271 (A First-in-Human Study of the Safety of Single Continuous Intravenous (IV) Infusions of CXL-1427 for up to 48 Hours in Healthy Volunteers)

  9. Drug

    Seltorexant

    go.drugbank.com/drugs/DB14961
    Investigational

    Seltorexant is under investigation in clinical trial NCT03494907 (A Study to Evaluate the Effects of Single-dose Seltorexant on Electrocardiogram Intervals in Healthy Adult Participants).

  10. Drug

    Avizakimab

    go.drugbank.com/drugs/DB18842
    Investigational

    Avizakimab is under investigation in clinical trial NCT03371251 (Study of BOS161721 in Systemic Lupus Erythematosus (SLE) Patients on a Background of Limited Standard of Care).