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Nimodipine
go.drugbank.com/drugs/DB00393ApprovedInvestigationalIt acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. … By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction.
Simvastatin
go.drugbank.com/drugs/DB00641ApprovedInvestigational[A181409,A181535,A181538,A1793] Potency is thought to correlate to tissue permeability as the more lipophilic statins such as simvastatin are thought to enter endothelial cells by passive diffusion, as … It belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid levels by inhibiting the endogenous production of cholesterol in the
Products: Nu-simvastatin TabletsEscitalopram
go.drugbank.com/drugs/DB01175ApprovedInvestigationalto other SSRIs. … as compared to other agents in this class.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: NEO ZENTIUS® 10 MG, NEO ZENTIUS® 20 MG COMPRIMIDOSCemiplimab
go.drugbank.com/drugs/DB14707ApprovedInvestigationalBy blocking PD-1, cemiplimab works to enhance T cell-mediated antitumour responses. … [L39804] Cemiplimab was also approved by the European Commission on June 28, 2019.
Palivizumab
go.drugbank.com/drugs/DB00110ApprovedInvestigationalHumanized monoclonal antibody (IgG1k) produced by recombinant DNA technology, directed to an epitope in the A antigenic site of the F protein of respiratory syncytial virus (RSV). … Palivizumab is composed of to heavy chains (50.6 kDa each) and two light chains (27.6 kDa each), contains 1-2% carbohydrate by weight and has a molecular weight of 147.7 kDa +/- 1 kDa (MALDI-TOF)
Amphetamine
go.drugbank.com/drugs/DB00182ApprovedIllicitInvestigational[A18540] The first product of Smith, Kline and French was approved by the FDA on 1976.[L5194] During World War II, amphetamine was used to promote wakefulness in the soldiers. … After being proven to reduce drug-induced anesthesia and produce arousal and insomnia, amphetamine racemic mix was registered by Smith, Kline and French in 1935.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeLymphoblastic Lymphoma
go.drugbank.com/conditions/DBCOND0032667Synonyms: Non-Hodgkin lymphoma, no ICD-O subtype, Non-Hodgkin lymphoma, no ICD-O subtype (morphologic abnormality)Diabetes Mellitus, Insulin Dependent
go.drugbank.com/conditions/DBCOND0035532Drugs: Insulin porkSynonyms: Diabetes mellitus: [juvenile type, with no mention of complication] or [insulin dependent]mRNA-1345
go.drugbank.com/drugs/DB18739ApprovedInvestigational[L53403,L52380] In June 2025, its US indication was expanded to include patients 18-59 years old at increased risk of disease. … mRESVIA was first approved in the EU and US in 2024 for use in patients 60 years of age and older.