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Doxycycline
go.drugbank.com/drugs/DB00254ApprovedInvestigationalVet approved[A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and malaria.[A251730] … Doxycycline is a broad-spectrum antibiotic synthetically derived from [oxytetracycline].[L42880] It is a second-generation tetracycline that was first discovered in 1967.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseInternational brands: Nu-DoxycyclineZuclopenthixol
go.drugbank.com/drugs/DB01624ApprovedInvestigationalIt is known that zuclopenthixol is metabolized by Cytochrome P450 2D6. Zuclopenthixol was approved for use in Canada in 2011, but is not approved for use in the United States. … Zuclopenthixol, also known as Zuclopentixol or Zuclopenthixolum, is an antipsychotic agent.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: CLOPIXOL-ACUPHASE INJ 50MG/ML (1ML), Clopixol Depot - Liq Im 200mg/mlRamucirumab
go.drugbank.com/drugs/DB05578ApprovedInvestigationalRamucirumab is indicated for us in advanced gastric or gastro-esophageal junction adenocarcinoma as a single agent or in combination with paclitaxel after prior fluoropyrimidine- or platinum-containing … VEGFR stimulation also mediates downstream signalling required for angiogenesis and is postulated to be heavily involved in cancer progression, making it a highly likely drug target.
Products: CYRAMZA CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/10ML, CYRAMZA CONCENTRATE FOR SOLUTION FOR INFUSION 500MG/50MLCanakinumab
go.drugbank.com/drugs/DB06168ApprovedInvestigationalClinical trials have established the administration of canakinumab every 2 weeks to be safe and effective, offering a considerable advantage over the existing treatment with the human IL-1 receptor antagonist … Canakinumab binds to human IL-1β and neutralizes its inflammatory activity by blocking its interaction with IL-1 receptors, but it does not bind IL-1alpha or IL-1 receptor antagonist (IL-1ra).
Products: ILARIS 150MG POWDER FOR SOLUTION FOR INJECTION, Ilaris Powder for Solution for Injection 150mg/vialTriclosan
go.drugbank.com/drugs/DB08604ApprovedIt is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards … An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group.
Mixtures: Colgate Total Clean in Between, QV FLARE UP BATH OILProducts: Stoko Refresh Antibacterial Foam Wash for 4 In 1 Dispensing System, Thera RxKetotifen
go.drugbank.com/drugs/DB00920ApprovedInvestigational[A231204] In the US, it is now used in an over-the-counter ophthalmic formulation for the treatment of itchy eyes associated with allergies,[L32278] and in Canada a prescription-only oral formulation is … available and indicated as an add-on therapy for children with atopic asthma.
Categories: Antihistamines for Systemic UseProducts: Zaditen konservierungsmittelfrei 0,025% - Augentropfen in Einzeldosisbehältnissen, Nu-ketotifen Syrup - 1mg/5mlFlupentixol
go.drugbank.com/drugs/DB00875ApprovedInvestigationalWithdrawnIt is approved for use in Canada and other countries around the world, but not in the US. … It is used for the management of chronic schizophrenia in patients whose main manifestations do not include excitement, agitation or hyperactivity.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: Fluanxol Depot Inj 20mg/ml, Fluanxol Depot Inj 100mg/mlZinc sulfate
go.drugbank.com/drugs/DB09322ApprovedInvestigationalIt is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system. … Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol".
Mixtures: Tricare Prenatal DHA One Rx Multivitamin, Rohto All-In-OneCategories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseCilastatin
go.drugbank.com/drugs/DB01597ApprovedInvestigationalCilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4. … Since the antibiotic, [imipenem], is one such antibiotic that is hydrolyzed by dehydropeptidase, cilastatin is used in combination with imipenem to prevent its metabolism.
Synonyms: (Z)-7-((R)-2-Amino-2-carboxy-ethylsulfanyl)-2-[((S)-2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acidMixtures: BACQURE FOR IV INJECTION 500MG, PREPENEM FOR IV INJECTION 500MGPentoxifylline
go.drugbank.com/drugs/DB00806ApprovedInvestigational[A226415, L30300] Although originally developed to treat intermittent claudication, a form of exertion-induced leg pain common in patients with peripheral arterial disease, PTX has been investigated for … [A226608] Pentoxifylline has been marketed in Europe since 1972; PTX extended-release tablets sold under the trade name TRENTAL by US Pharm Holdings were first approved by the FDA on Aug 30, 1984, but
International brands: Ao Le Ni, An Ruo NingCategories: Compounds used in a research, industrial, or household setting, Drugs for Obstructive Airway Diseases