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Apremilast
go.drugbank.com/drugs/DB05676ApprovedInvestigationalIt belongs to the same drug class as [Roflumilast] and [Crisaborole].[A181244,L7495] Initially approved in 2014, it is marketed by Celgene. … Apremilast, also known as Otezla, is a phosphodiesterase 4 (PDE4) inhibitor used to treat various types of symptoms resulting from certain inflammatory autoimmune diseases.
Categories: Antineoplastic and Immunomodulating AgentsProducts: Aprezo 20mg Film Coated Tablets, Aprezo 10mg Film Coated TabletsAsparaginase Escherichia coli
go.drugbank.com/drugs/DB00023ApprovedInvestigationalAsparaginase derived from _Escherichia coli_ (L-asparagine amidohydrolase, EC 3.5.1.1) is an enzyme responsible for the metabolism of L-asparagine, by catalyzing L-asparagine into L-aspartic acid and ammonia … Therapeutic L-asparaginase from _E. coli_ works by depleting the levels of non-essential amino acid, asparagine, in lymphoblastic leukemic cells thus promoting apoptotic cell death [A31999].
Categories: Enzymes and Coenzymes, Antineoplastic and Immunomodulating AgentsProducts: KIDROLASE 10000 UIArtemisia vulgaris root
go.drugbank.com/drugs/DB14170ApprovedArtemisia vulgaris root allergenic extract is used in allergenic testing.
Products: LAIS Beifuß 1000 UA SublingualtablettenCamphor
go.drugbank.com/drugs/DB01744ApprovedInvestigationalWithdrawnIt appears in the list of drug products withdrawn or removed from the market for safety or effectiveness. … It is used topically as a skin antipruritic and as an anti-infective agent.
Synonyms: Camphor D-formMixtures: Zam-Buk Ointment, NORAVER UAzithromycin
go.drugbank.com/drugs/DB00207ApprovedInvestigationalThis differentiates azithromycin from other types of macrolides [A174175]. … Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration [A174172]. It was initially approved by the FDA in 1991 [A174175].
Categories: cefixime and azithromycin, azithromycin, fluconazole and secnidazoleProducts: ZITHROMAX TR-SAFT K B 25KG, Zithromax - Pws Orl 100mg/5mlRizatriptan
go.drugbank.com/drugs/DB00953ApprovedInvestigational[L46018] Used in the treatment of migraines, rizatriptan was first approved in the US in 1998. … Rizatriptan is a second-generation triptan [A258918] and a selective 5-HT<sub>1B and 5-HT1D</sub> receptor agonist.
Categories: Serotonin-1b and Serotonin-1d Receptor AgonistProducts: MAXALT 10MG, MAXALT LINGUA 10MGEverolimus
go.drugbank.com/drugs/DB01590ApprovedInvestigationalEverolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor. … It is currently used as an immunosuppressant to prevent rejection of organ transplants.
Categories: Antineoplastic and Immunomodulating AgentsProducts: Afinitor Tablet 10mg, Afinitor 2.5mg TabletOndansetron
go.drugbank.com/drugs/DB00904ApprovedInvestigationalWithdrawnHaving been developed in the 1980s by GlaxoSmithKline and approved by the US FDA since January 1991, ondansetron has demonstrated a long history of use and efficacy. … It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Categories: Antiemetics and AntinauseantsProducts: Ondansetron and Dextrose, Ondansetron Hydrochloride and DextrosePegaspargase
go.drugbank.com/drugs/DB00059ApprovedInvestigationalHowever, using L-asparaginase derived from _Escherichia coli_ may cause hypersensitivity in some patients and require frequent administration. … Pegaspargase is a conjugate of monomethoxypolyethylene glycol (mPEG) and L-asparaginase (L-asparagine amidohydrolase), an asparagine-specific enzyme that converts L-asparagine into aspartic acid and ammonia
Categories: Enzymes and Coenzymes, Antineoplastic and Immunomodulating AgentsProducts: ONCASPAR ®3750 UI, ONCASPAR® 750 U/ML POLVO PARA SOLUCIÓN INYECTABLEMeclizine
go.drugbank.com/drugs/DB00737ApprovedInvestigationalMeclizine is a histamine H1 antagonist with antiemetic and antivertigo properties. … It also exhibits anticholinergic, central nervous system depressant, and local anesthetic effects.
Mixtures: VELOXIN TABLET 25/50mgProducts: VERMEC® 25MG, Bonamine Tab 25mg Chewable