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Guanfacine
go.drugbank.com/drugs/DB01018ApprovedInvestigationalGuanfacine, or BS 100-141,[A189838,A189841] is a selective alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension[L11274] but is now indicated as an extended release … [L11277] Guanfacine was first described in the literature in 1974.[A189841] Guanfacine was granted FDA approval on 27 October 1986.[L11274]
Categories: Adrenergic alpha-2 Receptor Agonists, Central alpha-2 Adrenergic AgonistProducts: ARİSLOW ER 2 MG UZATILMIŞ SALIMLI TABLET, 28 TABLET, ARİSLOW ER 4 MG UZATILMIŞ SALIMLI TABLET, 28 TABLETVon Willebrand factor human
go.drugbank.com/drugs/DB13133ApprovedInvestigationalIt serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood vessel injury and stabilizing procoagulant factor VIII (FVIII). … The human vWF is used to manage and control bleeding episodes in patients with von Willebrand disease and hemophilia A. It was first approved by the FDA in 2015.
Mixtures: BIOSTATE FOR INJECTION 50 iu/ml, Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for InjectionCategories: von Willebrand factor and coagulation factor VIII in combinationBedaquiline
go.drugbank.com/drugs/DB08903ApprovedInvestigational[A261856] Currently, bedaquiline is the last-line anti-TB drug and must only be used in an appropriate combination regimen.[L48506,A261866] … [A261856,A261861] It is the first drug that was approved in the last 40 years by the FDA for TB unresponsive to current treatments on the market.
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesSynonyms: 1-(6-Bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-naphthalen-1-yl-1-phenyl-butan-2-olDinoprostone
go.drugbank.com/drugs/DB00917ApprovedInvestigationalDinoprostone is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour. It also stimulates osteoblasts to release factors which stimualtes bone resorption by osteoclasts. … As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce labour.
Categories: Prostaglandins ESynonyms: (Z)-7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid, (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acidHepatitis B Vaccine (Recombinant)
go.drugbank.com/drugs/DB11627ApprovedInvestigationalWithdrawnIn Canada, the United States and Northern Europe, 4% to 6% of the population are infected during their lifetime (mostly young adults); between 5% and 10% of infections lead to persistent viremia (carrier … In Asia, infection often occurs early in life, leading to a hepatitis B marker prevalence of more than 70% in the general population and a carrier rate of up to 20%.
Mixtures: HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 10 ADET, HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 10 ADETProducts: ENGERIX-B PEDIYATRIK 10 MCG/0,5 ML IM ENJEKSİYON İÇİN SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTOR, 50 DOZ, ENGERIX-B 10 Mikrogramm/0,5 ml Injektionssuspension in einer FertigspritzeAlprazolam
go.drugbank.com/drugs/DB00404ApprovedIllicitInvestigational[A18125] Alprazolam was given FDA approval on October 16, 1981.[L6148] … [A18125] Alprazolam's adverse effects are generally related to the sedation it can cause.
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesProducts: ALPRAZOLAM EG, Alprazolam ERNeostigmine
go.drugbank.com/drugs/DB01400ApprovedInvestigationalVet approvedA cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine.
Synonyms: m-Trimethylammoniumphenyldimethylcarbamate, (m-Hydroxyphenyl)trimethylammonium dimethylcarbamateProducts: PLANTIGMIN 0,5 MG/ML ENJEKSİYONLUK ÇÖZELTİ, 100 ADET, PLANTIGMIN 0,5 MG/ML ENJEKSİYONLUK ÇÖZELTİ, 50 ADETCisatracurium
go.drugbank.com/drugs/DB00565ApprovedInvestigational[A243416,A253592] Cisatracurium has an intermediate duration of action and is one of the most commonly used neuromuscular blocking agents in intensive care.[A253592,A253597]. … Cisatracurium is a non-depolarising neuromuscular blocking agent of the benzylisoquinolinium class, available in its salt form, cisatracurium besylate.
Synonyms: (1r,2r,1'r,2'r)-2,2'-{pentane-1,5-diylbis[oxy(3-oxopropane-3,1-diyl)]}bis[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinium]Categories: Heterocyclic Compounds, 2-RingMilrinone
go.drugbank.com/drugs/DB00235ApprovedInvestigationalHeart failure is a multifactorial condition that affects roughly 1-2% of the adult population. … [A228338, A11759, A228323, A228333, A228348, L31483] Milrinone was originally synthesized at the Sterling Winthrop Research Institute in the 1980s.
Mixtures: Milrinone Lactate in DextroseCategories: Compounds used in a research, industrial, or household settingFluoride ion F-18
go.drugbank.com/drugs/DB09398ApprovedInvestigationalIt contains radioactive fluoride F 18 that is used for diagnostic purposes in conjunction with positron emission tomography (PET) imaging and is administered by intravenous injection. … Increased deposition around joints can occur in arthritis and following trauma and increased deposition in bone has been noted around fracture sites, in osteomyelitis, fibrous dysplasia, spondylitis tuberculosa
Products: DENTİFLOUR 0.25 MG TABLET, 100 ADET, SODIUM FLUORIDE F18 INJECTION 10-200 mCi/ml