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Ketobemidone
go.drugbank.com/drugs/DB06738InvestigationalKetobemidone is a powerful opioid analgesic. It also has some NMDA-antagonist properties. This makes it useful for some types of pain that don't respond well to other opioids. … The most commonly cited equalisation ratio for analgesic doses is 25 mg of ketobemidone hydrobromide to 60 mg of morphine hydrochloride or sulfate and circa 8 mg of ketobemidone by injection.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesSeratrodast
go.drugbank.com/drugs/DB06739ExperimentalSeratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 InhibitorsGinkgolide A
go.drugbank.com/drugs/DB06743ExperimentalNutraceuticalGinkgolide A is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. Shows potential in a wide variety of inflammatory and immunological disorders.
Synonyms: Ginkgolide-AGinsenoside C
go.drugbank.com/drugs/DB06748ExperimentalNutraceuticalCategories: Cytochrome P-450 CYP2C19 Inhibitors, Cytochrome P-450 Enzyme InhibitorsPinacidil
go.drugbank.com/drugs/DB06762ApprovedPinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTetryzoline
go.drugbank.com/drugs/DB06764Approved[A231769] Available since the 1950s, tetryzoline is a selective α<sub>1</sub>-receptor agonist [A231774] that is used as an ocular and nasal decongestant. … Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral alpha (α)-adrenergic properties.
Mixtures: FLU-SURE T® SUSPENSIÓN OFTÁLMICA, ISCHEMOL ACategories: Adrenergic alpha-1 Receptor Agonists, Heterocyclic Compounds, 1-RingAlcaftadine
go.drugbank.com/drugs/DB06766ApprovedAlcaftadine is a H1 histamine receptor antagonist indicated for the prevention of itching associated with allergic conjunctivitis. This drug was approved in July 2010.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingProducts: LASTACAFT®, LASTACAFT % 0,25 GÖZ DAMLASI, ÇÖZELTİ, 1 ADETBenzyl alcohol
go.drugbank.com/drugs/DB06770ApprovedInvestigationalMixtures: Itch-X, Itch XCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesHuman calcitonin
go.drugbank.com/drugs/DB06773ApprovedCalcitonin was first discovered in isolated parathyroid tissue as a substance with a serum-calcium-lowering effect. … [A32099] It is constituted as a 32-amino acid single chain polypeptide structure that gets secreted as a regulatory agent in calcium-phosphorus metabolism.
Capsaicin
go.drugbank.com/drugs/DB06774ApprovedInvestigationalCapsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations. … The most recent capsaicin FDA approval was Qutenza, an 8% capsaicin patch dermal-delivery system, indicated for neuropathic pain associated with post-herpetic neuralgia.
Mixtures: Med O-3 Bio-, s CreamCategories: Cytochrome P-450 Substrates, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates