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Telisotuzumab adizutecan
go.drugbank.com/drugs/DB21832InvestigationalTelisotuzumab Adizutecan is under investigation in clinical trial NCT06614192 (A Study Assessing Adverse Events and Disease Activity When Comparing Intravenously (IV) Infused ABBV-400 to Trifluridine and
Zoracopan
go.drugbank.com/drugs/DB21702InvestigationalZoracopan is under investigation in clinical trial NCT06173596 (A Study to Evaluate Potential Drug Interactions Between ALXN2080 and Itraconazole, Fluconazole & Carbamazepine in Healthy Adults).
Ketanserin
go.drugbank.com/drugs/DB12465InvestigationalKetanserin has been investigated for the treatment of Septic Shock, Severe Sepsis, and Diabetic Foot Ulcer.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeBiochanin A
go.drugbank.com/drugs/DB15334ExperimentalBiochanin A is under investigation in clinical trial NCT02174666 (Isoflavone Treatment for Postmenopausal Osteopenia.).
Categories: Estrogens, Non-SteroidalProscillaridin
go.drugbank.com/drugs/DB13307ExperimentalStudies suggest the potential cytotoxic and anticancer property of proscillaridin, based on evidence of the drug potently disrupting topoisomerase I and II activity at nanomolar drug concentrations [A27193
Casdatifan
go.drugbank.com/drugs/DB21701InvestigationalCasdatifan is under investigation in clinical trial NCT07000149 (A Study to Investigate the Efficacy and Safety of Volrustomig ± Casdatifan vs Nivolumab + Ipilimumab as 1L Treatment for Advanced ccRCC)
Tegtociclib
go.drugbank.com/drugs/DB21635InvestigationalTegtociclib is under investigation in clinical trial NCT05262400 (A Study to Learn About the Study Medicine (Called PF-07220060 in Combination With PF-07104091) In Participants With Breast Cancer and Solid
GC-376 free acid
go.drugbank.com/drugs/DB15796ExperimentalA prodrug of [GC-373], GC-376 has recently been used to test inhibition of SARS-Cov-2 M<sup>pro</sup> _in vitro_, and results show potent inhibition of this target[A219036]. … The compound is known as a direct acting antiviral (DAA) for coronaviruses, and was initially developed using structure-guided design to combat MERS-Cov infections[A219036,A219056].