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Metacycline
go.drugbank.com/drugs/DB00931ApprovedA broad-spectrum semisynthetic antibiotic related to tetracycline but excreted more slowly and maintaining effective blood levels for a more extended period.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseBaloxavir marboxil
go.drugbank.com/drugs/DB13997ApprovedInvestigational[A251760] Baloxavir marboxil was first globally approved in Japan in February 2018,[A39895] followed by the US approval in October, 2018. … [L4779] It was also approved by the European Commission on January 7, 2021.[L45241]
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseLornoxicam
go.drugbank.com/drugs/DB06725ApprovedInvestigationalLornoxicam is approved for use in Japan.
Hydrocodone
go.drugbank.com/drugs/DB00956ApprovedIllicitInvestigationalThe FDA first approved Hydrocodone for use as part of the cough suppressant syrup Hycodan in March of 1943.[L9025] … Hydrocodone's more potent metabolite, [hydromorphone] has also found wide use as an analgesic and is frequently used in cases of severe pain.
Benzoyl peroxide
go.drugbank.com/drugs/DB09096ApprovedInvestigationalBenzoyl peroxide is a commonly used drug in topical treatments for acne. It has been formulated as products with either a single active ingredient, or with erythromycin, clindamycin, or adapalene. After administration, the peroxide bond ...
Categories: Anti-Acne Preparations for Topical UseProducts: Benzac W10 Gel 10% USPCeftobiprole medocaril
go.drugbank.com/drugs/DB14733ApprovedThe EMA's Committee for Medicinal Products for Human Use (CHMP) adopted a negative opinion of ceftobiprole medocaril in February 2010, recommending the refusal of its marketing authorization in the European … [L50467] It received its first approval in Canada in October 2017 for use in certain patients with bacterial pneumonia,[L50472] and was subsequently approved in the United States with additional indications
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseReserpine
go.drugbank.com/drugs/DB00206ApprovedWithdrawnIt has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use. … The FDA withdrew its approval for the use of all oral dosage form drug products containing more than 1 mg of reserpine.[L43942]
Mafenide
go.drugbank.com/drugs/DB06795ApprovedVet approvedWithdrawnIn November 2022, the use of mafenide acetate (powder for 5% topical solution) was withdrawn by the FDA due to an unresolved confirmatory study required to fulfill the accelerated approval requirements … It acts by reducing the bacterial population present in the burn tissue and promotes healing of deep burns.
Atorvastatin
go.drugbank.com/drugs/DB01076ApprovedInvestigationalThe evidence supporting statin use, coupled with minimal side effects and long term benefits, has resulted in wide use of this medication in North America. … [A181397, A181403] Atorvastatin was first synthesized in 1985 by Dr. Bruce Roth and approved by the FDA in 1996.
Potassium nitrate
go.drugbank.com/drugs/DB11090ApprovedInvestigationalPotassium nitrate is an inorganic salt with a chemical formula of KNO3. It is a natural source of nitrate and has been used as a constituent for several different purposes, including food preservatives, fertilizers, tree stump removal, r...
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