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Displaying results 721 - 730 of 10000 in total
  1. Drug

    Interferon beta-1a

    go.drugbank.com/drugs/DB00060
    ApprovedInvestigational

    It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced. … The amino acid sequence is identical to that of natural human interferon beta.

    Synonyms: Interferon beta 1-a, IFN β-1aCategories: Interferon Type I, Cytochrome P-450 CYP1A2 Inhibitors
  2. Drug

    Rifampin

    go.drugbank.com/drugs/DB01045
    ApprovedInvestigational

    [A263768] Rifampin is used to treat tuberculosis and works by inhibiting the microbial DNA-dependent RNA polymerase (RNAP).[A263768] … Rifampin, also known as rifampicin, is a broad-spectrum antimicrobial [A263748] that was first discovered in 1965 [A263753] and clinically used in 1968.

    Synonyms: 5,6,9,17,19,21-Hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-[N-(4-methyl-1-piperazinyl)formimidoyl]-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione 21-acetate, 3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SVMixtures: RINCURE ® 3 FDC TABLETAS CON PELICULA, DOTBAL-S
  3. Drug

    Alprazolam

    go.drugbank.com/drugs/DB00404
    ApprovedIllicitInvestigational

    [A18125] Alprazolam's adverse effects are generally related to the sedation it can cause. … [L34783, L34788] It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like ketoconazole and itraconazole.

    Mixtures: NEUPAX DUO-SCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-Ring
  4. Drug

    Tetryzoline

    go.drugbank.com/drugs/DB06764
    Approved

    [A7045, A231769] It has also been misused for non-therapeutic purposes as a causative drug for several cases of drug-facilitated sexual assault.[A231764] … [A231769] Available since the 1950s, tetryzoline is a selective α<sub>1</sub>-receptor agonist [A231774] that is used as an ocular and nasal decongestant.

    Synonyms: 2-(1,2,3,4-Tetrahydro-1-naphthyl)-2-imidazoline, 2-Tetralin-1-yl-4,5-dihydro-1H-imidazoleMixtures: Up and Up Ultra Itchy Relief, SK Advanced Relief Eye Drops
  5. Drug

    PBCAR269A

    go.drugbank.com/drugs/DB17188
    Investigational

    Synonyms: Allogeneic gene edited BCMA-directed CAR T cells
  6. Drug

    Atenolol

    go.drugbank.com/drugs/DB00335
    ApprovedInvestigational

    Atenolol itself was developed early on in this history by Alvogen Malta under the trade name Tenormin and received FDA approval in September, 1981. … Later they continued to be investigated for use in heart failure throughout the 1970-1980s.

    Synonyms: 1-p-Carbamoylmethylphenoxy-3-isopropylamino-2-propanol, 2-(p-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamideMixtures: ATENOLOL CO RATIO 100/25MG, PLENACOR D
  7. Drug

    Mometasone furoate

    go.drugbank.com/drugs/DB14512
    ApprovedInvestigationalVet approved

    Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295]. … Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different indications[FDA Label][F4292,F4295].

    Mixtures: M-FURO FA %0.1 + %2 KREM, 30 G, DERMOTIL-S® UNGUENTOCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers
  8. Indication

    Ependymoma

    go.drugbank.com/conditions/DBCOND0017183
    Drugs: Carmustine
    Synonyms: Ependymoma, no ICD-O subtype, Ependymoma, no ICD-O subtype (morphologic abnormality)
  9. Drug

    Hydroxychloroquine

    go.drugbank.com/drugs/DB01611
    ApprovedInvestigational

    Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer.[A183047] Hydroxychloroquine is an aminoquinoline like [chloroquine]. … [L14312]** Hydroxychloroquine was granted FDA approval on 18 April 1955.[L8072] A recent study reported a fatality in the group being treated with hydroxychloroquine for COVID-19.[A192546]

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: 7-chloro-4-[5-(N-ethyl-N-2-hydroxyethylamino)-2-pentyl]aminoquinoline, 7-chloro-4-(4-(N-ethyl-N-β-hydroxyethylamino)-1-methylbutylamino)quinoline
  10. Indication

    Medulloblastomas

    go.drugbank.com/conditions/DBCOND0032185
    Drugs: Carmustine
    Synonyms: Medulloblastoma, no ICD-O subtype, Medulloblastoma, no International Classification of Diseases for Oncology subtype