NCT06607692
Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined with the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed). treatment 2 recruiting NCT06639607
PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and Ependymoma No drug interventions treatment 1 / 2 not_yet_recruiting NCT01445288
Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors No drug interventions Not Available Not Available completed NCT03389802
Phase I Study of APX005M in Pediatric Central Nervous System Tumors treatment 1 active_not_recruiting NCT03990597
StrataXRT in Preventing Radiation Dermatitis in Pediatric Patients Undergoing Radiation Therapy to the Brain or Spinal Cord No drug interventions supportive_care 1 withdrawn NCT00336024
Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma treatment 3 active_not_recruiting NCT03173950
Immune Checkpoint Inhibitor Nivolumab in People With Recurrent Select Rare CNS Cancers treatment 2 recruiting NCT06624371
Atovaquone Combined with Radiation in Children with Malignant Brain Tumors treatment 1 recruiting NCT06161519
PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications No drug interventions treatment 1 / 2 recruiting NCT05382338
A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss treatment 3 suspended NCT05535166
Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma treatment 2 recruiting NCT00601003
Study of Nifurtimox to Treat Refractory or Relapsed Neuroblastoma or Medulloblastoma treatment 2 completed NCT00031590
Low-Dose Radiation and Combination Chemotherapy Following Surgery in Children With Newly Diagnosed Medulloblastoma treatment 2 terminated NCT04315064
Infusion of Panobinostat (MTX110) Into the Fourth Ventricle in Children and Adults With Recurrent Medulloblastoma No drug interventions treatment 0 recruiting NCT04337177
Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors treatment 1 recruiting NCT02681705
Radiation Therapy and Combination Chemotherapy for Medulloblastoma treatment 2 unknown_status NCT00867178
Vorinostat Combined With Isotretinoin and Chemotherapy in Treating Younger Patients With Embryonal Tumors of the Central Nervous System treatment 1 completed NCT02624388
Study of Genistein in Pediatric Oncology Patients (UVA-Gen001) supportive_care 2 terminated NCT02162732
Molecular-Guided Therapy for Childhood Cancer No drug interventions treatment Not Available completed NCT01351870
Hyperfractionated Versus Conventionally Fractionated Radiotherapy in Standard Risk Medulloblastoma No drug interventions treatment 3 completed NCT04730349
A Study of Bempegaldesleukin (BEMPEG: NKTR-214) in Combination With Nivolumab in Children, Adolescents and Young Adults With Recurrent or Treatment-resistant Cancer treatment 1 / 2 terminated NCT00520936
A Study of Pemetrexed in Children With Recurrent Cancer treatment 2 completed NCT06499636
In Vitro Models From Pediatric Brain Tumors No drug interventions Not Available Not Available not_yet_recruiting NCT03734913
A Phase 1 Study of ZSP1602 in Participants With Advanced Solid Tumors No drug interventions treatment 1 unknown_status NCT01975116
p28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System Tumors treatment 1 completed NCT05106296
Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer treatment 1 recruiting NCT01331135
Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors treatment 1 completed NCT05125666
Efficacy of Dual Task Training on Children With Ataxia After Medulloblastoma Resection No drug interventions treatment 2 unknown_status NCT01619865
Safety of 68Ga-DOTA-tyr3-Octreotide PET in Diagnosis of Solid Tumors diagnostic 1 / 2 completed NCT02212574
Study Assessing the Feasibility of a Surgery and Chemotherapy-Only in Children With Wnt Positive Medulloblastoma treatment 0 terminated NCT01708174
A Phase II Study of Oral LDE225 in Patients With Hedge-Hog (Hh)-Pathway Activated Relapsed Medulloblastoma (MB) treatment 2 completed NCT01208831
An East Asian Study of LDE225 treatment 1 completed NCT03257631
A Study of Pomalidomide Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors treatment 2 completed NCT04402073
Personalized Risk-Adapted Therapy in Post-Pubertal Patients With Newly-Diagnosed Medulloblastoma health_services_research 2 active_not_recruiting NCT00392327
Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma/PNET treatment 3 active_not_recruiting NCT02747576
Social Cognition and Brain Integrity in Survivors of Pediatric Medulloblastoma No drug interventions Not Available Not Available completed NCT03500991
HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors No drug interventions treatment 1 active_not_recruiting NCT00180791
High Risk Primitive Neuroectodermal (PNET) Brain Tumors in Childhood treatment 2 unknown_status NCT02644291
Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumors treatment 1 completed NCT03434262
SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors treatment 1 completed NCT02441062
Impact of Ga-68 DOTATOC PET-CT Imaging in Management of Neuroendocrine Tumors diagnostic 2 completed NCT03709680
Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors treatment 1 / 2 active_not_recruiting NCT03581240
An Intermediate Expanded Use Trial of DFMO Not Available Not Available available NCT03638167
EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors No drug interventions treatment 1 active_not_recruiting NCT04081701
68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors. No drug interventions diagnostic 4 recruiting NCT04023669
Evaluation of LY2606368 Therapy in Combination With Cyclophosphamide or Gemcitabine for Children and Adolescents With Refractory or Recurrent Group 3/Group 4 or SHH Medulloblastoma Brain Tumors treatment 1 active_not_recruiting NCT01171469
Vaccination With Dendritic Cells Loaded With Brain Tumor Stem Cells for Progressive Malignant Brain Tumor treatment 1 completed NCT04049669
Pediatric Trial of Indoximod with Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG treatment 2 recruiting NCT01505569
Auto Transplant for High Risk or Relapsed Solid or CNS Tumors other Not Available completed NCT04521946
Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer treatment 1 withdrawn NCT06396481
Clinical Study of Allogeneic Vγ9Vδ2 T Cells in the Treatment of Brain Malignant Glioma No drug interventions treatment 0 not_yet_recruiting NCT00404495
Combination of Irinotecan and Temozolomide in Children With Brain Tumors. treatment 2 completed NCT01063114
Proton Beam Radiotherapy for Medulloblastoma and Pineoblastoma No drug interventions treatment Not Available active_not_recruiting NCT06485908
Axitinib and Oral Metronomic Etoposide for Pediatric Children and AYA Refractory/Relapsing Medulloblastoma and Ependymoma treatment 1 / 2 not_yet_recruiting NCT00880308
Dose Finding and Safety of Oral LDE225 in Patients With Advanced Solid Tumors treatment 1 completed NCT05672043
Genetic and Molecular Risk Profiles of Pediatric Malignant Brain Tumors in China No drug interventions Not Available Not Available recruiting NCT05128903
Quantitative Assessment of Radiation-induced Neuroinflammation - A Proof of Principle Study No drug interventions diagnostic 2 active_not_recruiting NCT01861990
Valproic Acid in Childhood Progressive Brain Tumors treatment 1 withdrawn NCT02017964
Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed, Non-metastatic Desmoplastic Medulloblastoma treatment 2 completed NCT00001502
A Pediatric Phase I Trial of RMP-7 and Carboplatin in Brain Tumors treatment 1 completed NCT05057702
Individualized Treatment Plan in Children and Young Adults With Relapsed Medulloblastoma No drug interventions other Not Available recruiting NCT04661384
Brain Tumor-Specific Immune Cells (IL13Ralpha2-CAR T Cells) for the Treatment of Leptomeningeal Glioblastoma, Ependymoma, or Medulloblastoma No drug interventions treatment 1 recruiting NCT02724579
Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma treatment 2 active_not_recruiting NCT03013387
Dosimetry Guided PRRT With 90Y-DOTATOC treatment 2 withdrawn NCT05835687
Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors No drug interventions treatment 1 recruiting NCT00407433
Clinical Studies of Gemcitabine-Oxaliplatin treatment 2 completed NCT01857453
Interest of a Dose Decrease for Radiotherapy Associated With Chemotherapy for Treatment of Standard Risk Adult Medulloblastomas treatment 2 unknown_status NCT00840047
Methionine PET/CT Studies In Patients With Cancer diagnostic 2 recruiting NCT00983398
Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors treatment 1 / 2 unknown_status NCT04270461
NKG2D-based CAR T-cells Immunotherapy for Patient With r/r NKG2DL+ Solid Tumors treatment 1 withdrawn NCT03583528
DOTATOC PET/CT for Imaging NET Patients No drug interventions Not Available Not Available recruiting NCT00994071
A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors treatment 1 completed NCT01614132
Multicenter Pilot-study for the Therapy of Medulloblastoma of Adults treatment 1 / 2 completed NCT01125800
A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MB treatment 1 / 2 completed NCT02689336
Erlotinib in Combination With Temozolomide in Treating Relapsed/Recurrent/Refractory Pediatric Solid Tumors treatment 2 withdrawn NCT01878617
A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma treatment 2 active_not_recruiting NCT04334863
WP1066 in Children With Refractory and Progressive or Recurrent Malignant Brain Tumors treatment 1 completed NCT05131763
NKG2D-based CAR T-cells Immunotherapy for Patient With r/r NKG2DL+ Solid Tumors treatment 1 unknown_status NCT03675230
Study of Tomotherapy HD in Medulloblastoma No drug interventions treatment Not Available unknown_status NCT05934630
Testing Cerebrospinal Fluid for Cell-free Tumor DNA in Children, Adolescents, and Young Adults With Brain Tumors No drug interventions Not Available Not Available active_not_recruiting NCT01483820
Safety and Efficacy Study of TPI-287 in Neuroblastoma and Medulloblastoma treatment 1 / 2 terminated NCT04541082
Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms No drug interventions treatment 1 recruiting NCT04978727
A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma treatment 1 recruiting NCT03043391
Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children treatment 1 completed NCT04696029
DFMO as Maintenance Therapy for Molecular High/Very High Risk and Relapsed Medulloblastoma treatment 2 recruiting NCT03251989
Rare CNS Tumors Outcomes &Risk No drug interventions Not Available Not Available suspended NCT02332889
Phase I/II: Decitabine/Vaccine Therapy in Relapsed/Refractory Pediatric High Grade Gliomas/Medulloblastomas/CNS PNETs treatment 1 / 2 terminated NCT01802567
Molecular-Guided Therapy for Relapsed and Refractory Childhood Cancer No drug interventions treatment Not Available completed NCT01326104
Vaccine Immunotherapy for Recurrent Medulloblastoma and Primitive Neuroectodermal Tumor No drug interventions treatment 2 active_not_recruiting NCT00867568
TPI 287 in Patients With Refractory or Recurrent Neuroblastoma or Medulloblastoma treatment 1 completed NCT03273712
Dosimetry-Guided, Peptide Receptor Radiotherapy (PRRT) With 90Y-DOTA- tyr3-Octreotide (90Y-DOTATOC) treatment 2 completed NCT00231712
Immuno 1: Immune Reconstitution Following Conventional or High-Dose Chemotherapy With Stem Cell Transplant No drug interventions Not Available Not Available unknown_status NCT02875314
HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors treatment 4 active_not_recruiting NCT05278208
Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors treatment 1 / 2 recruiting NCT06323408
Integrated Analysis of Therapy Response and Resistence in Embryonal Tumors and Gliomas No drug interventions Not Available Not Available not_yet_recruiting NCT02502708
Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors treatment 1 completed NCT02441088
Theranostics: 68GaDOTATOC and 90YDOTATOC treatment 2 active_not_recruiting NCT04269343
Infusion of Panobinostat (MTX110) Into the Fourth Ventricle or Tumor Resection Cavity in Children and Adults With Recurrent Medulloblastoma No drug interventions treatment 0 not_yet_recruiting NCT00180947
Study of Vinorelbine and Cyclofosfamide Among Patients With Refractory Tumours or in Relapse treatment 2 unknown_status NCT00749723
Therapy Optimization Trial for the Treatment of Relapsed or Refractory Brain Tumors in Children treatment 2 / 3 completed