Search

Displaying results 721 - 730 of 1809 in total
  1. Target

    Interferon alpha/beta receptor (IFNAR)

    go.drugbank.com/bio_entities/BE0010136
    TargetHumans

    Together with IFNAR2, forms the heterodimeric receptor for type I interferons (including interferons alpha, beta, epsilon, omega and kappa) (PubMed:10049744, PubMed:14532120, PubMed:15337770, PubMed:2153461 … Can also act independently of IFNAR2: form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity)

    Polypeptides: Interferon alpha/beta receptor 1, Interferon alpha/beta receptor 2Synonyms: IFN-alpha/beta receptor 1, IFN-alpha/beta receptor 2
  2. Target

    Interleukin-1 receptor-like 2

    go.drugbank.com/bio_entities/BE0010198
    TargetHumans

    Receptor for interleukin-36 (IL36A, IL36B and IL36G). … After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways

    Polypeptides: Interleukin-1 receptor-like 2Synonyms: IL-36 receptor, Interleukin-1 receptor-related protein 2
  3. Target

    Interleukin-7 receptor subunit alpha

    go.drugbank.com/bio_entities/BE0010557
    TargetHumans

    Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP)

    Polypeptides: Interleukin-7 receptor subunit alphaSynonyms: IL-7 receptor subunit alpha
  4. Target

    Sphingosine 1-phosphate receptor 2

    go.drugbank.com/bio_entities/BE0012208
    TargetHumans

    Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P) (PubMed:10617617, PubMed:25274307). … Receptor for the chemokine-like protein FAM19A5 (PubMed:29453251). Mediates the inhibitory effect of FAM19A5 on vascular smooth muscle cell proliferation and migration (By similarity).

    Polypeptides: Sphingosine 1-phosphate receptor 2Synonyms: S1P receptor 2, S1P receptor Edg-5
  5. Target

    N-formyl peptide receptor 2

    go.drugbank.com/bio_entities/BE0012843
    TargetHumans

    Differential signaling is also defined by receptor oligomerization state. … Participates in neuroprotection via interaction with humanin/MT-RNR2 and Amyloid-beta protein 42, product of APP (PubMed:11689470, PubMed:35365641).

    Polypeptides: N-formyl peptide receptor 2Synonyms: LXA4 receptor, Lipoxin A4 receptor
  6. Drug

    Inositol

    go.drugbank.com/drugs/DB13178
    ApprovedInvestigationalWithdrawn

    Inositol is a collection of nine different stereoisomers but the name is usually used to describe only the most common type of inositol, myo-inositol. Myo-inositol is the cis-1,2,3,5-trans-4,6-cyclohexanehexol and it is prepared from an ...

    Mixtures: Vita Plex Tab, Vita-B
  7. Indication

    Non-venereal endemic syphilis

    go.drugbank.com/conditions/DBCOND0025727
    Drugs: Procaine benzylpenicillin
    Synonyms: Bejel
  8. Drug

    Vorinostat

    go.drugbank.com/drugs/DB02546
    ApprovedInvestigational

    A recent study suggested that vorinostat also possesses some activity against recurrent glioblastoma multiforme, resulting in a median overall survival of 5.7 months (compared to 4 - 4.4 months in earlier

  9. Drug

    Cefazolin

    go.drugbank.com/drugs/DB01327
    ApprovedInvestigational

    It attains high serum levels and is excreted quickly via the urine.

    Products: RECEF
  10. Drug

    Benzoic acid

    go.drugbank.com/drugs/DB03793
    ApprovedInvestigational

    Recent research shows that sodium benzoate may be beneficial as an add-on therapy (1 gram/day) in schizophrenia. Total Positive and Negative Syndrome Scale scores dropped by 21% compared to placebo.