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Acebutolol
go.drugbank.com/drugs/DB01193ApprovedInvestigationalThe drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action. … A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors.
Synonyms: N-(3-acetyl-4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl)butanamide, N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]butanamideCategories: acebutolol and thiazides, Beta Blocking Agents and ThiazidesMidostaurin
go.drugbank.com/drugs/DB06595ApprovedInvestigationalIt was approved on April 28, 2017 and has shown to increase the overall survival rate in patients with AML as an adjunct therapy along with chemotherapeutic agents. … It was initially characterized as a potential broad-spectrum antineoplastic agent, with activity toward diverse solid and hematopoietic tumors [A19108].
Synonyms: 4'-N-benzoylstaurosporineCategories: Antineoplastic and Immunomodulating AgentsCoagulation Factor IX (Recombinant)
go.drugbank.com/drugs/DB00100ApprovedIt is not derived from human blood (unlike human Factor IX complex), and is instead produced by a genetically engineered Chinese hamster ovary (CHO) cell line that secretes recombinant Factor IX into cell … It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX.
Products: BeneFIX Powder and Solvent for Solution for Injection 250iu/vial, BeneFIX Powder and Solvent for Solution for Injection 1000iu/vialDaratumumab
go.drugbank.com/drugs/DB09331ApprovedInvestigationalDaratumumab is an immunoglobulin G1 kappa monoclonal antibody developed by Janssen and Genmab. … This approval was based on results from the Phase 3 PERSEUS study, which demonstrated significant improvement in progression-free survival and higher rates of minimal residual disease (MRD) negativity
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: Darzalex 20mg/mL Concentrate for Solution for Infusion, DARZALEX CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/5MLPropylene glycol
go.drugbank.com/drugs/DB01839ApprovedInvestigationalA clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
Mixtures: Salinol Sol 160mg, Systane Day and Night Value PackProducts: Eyelash and Eyebrow Lengthener, RITE AID Lubricant DropsIrinotecan
go.drugbank.com/drugs/DB00762ApprovedInvestigational[A263376] Approved by the FDA in 1996,[A263366] irinotecan is used to treat colorectal cancer and pancreatic adenocarcinoma. … Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking its enzymatic activity, thereby interfering with DNA synthesis.
Categories: Antineoplastic and Immunomodulating AgentsProducts: TARCKORIN ® 100MG, Brinotec injection 20mg/mlDrotaverine
go.drugbank.com/drugs/DB06751ApprovedWithdrawnDrotaverine is an antispasmodic drug that works by inhibiting phosphodiesterase-4 (PDE4). … [A231619] Drotaverine is not approved by the FDA, European Medicines Agency, or Health Canada. It is approved for use in Thailand as oral tablets or intramuscular injections.[L22689]
Categories: Alimentary Tract and Metabolism, Papaverine and DerivativesInternational brands: No-SpaMitomycin
go.drugbank.com/drugs/DB00305ApprovedInvestigational[L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations, RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix. … Mitomycin is an antineoplastic antibiotic first isolated by Japanese microbiologists in the 1950s from cultures of _Streptomyces caespitosus_.
Categories: Indicators and Reagents, Antineoplastic and Immunomodulating AgentsProducts: Mutamycin Inj 20mg/vial, ALPHAMYCINA® 20MG POLVO LIOFILIZADO PARA INYECCIÓNThiotepa
go.drugbank.com/drugs/DB04572ApprovedInvestigationalIt is a stable derivative of N,N',N''- triethylenephosphoramide (TEPA). It is mostly used to treat breast cancer, ovarian cancer and bladder cancer. … N,N'N'-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group, now in use for over 50 years.
Synonyms: N,N′,N′′-tri-1,2-ethanediyl-, Phosphorothioic triamide, N,N′,N′′-tri-1,2-ethanediyl-Categories: Antineoplastic and Immunomodulating AgentsStyphnolobium japonicum flower bud
go.drugbank.com/drugs/DB14294InvestigationalStyphnolobium japonicum flower bud is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: Huai Flower Bud, Huaihua (Flower Bud)Products: BARAMO for O ily Scalp, BARAMO Scalp Serum for O ily Scalp