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Lidocaine
go.drugbank.com/drugs/DB00281ApprovedInvestigationalVet approvedEver since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication [T583]. … Regardless, lidocaine is currently available as a relatively non-expensive generic medication that is written for in millions of prescriptions internationally on a yearly basis.
Mixtures: EZ-Relief, Lidothol ESSynonyms: 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamideIdelalisib
go.drugbank.com/drugs/DB09054ApprovedInvestigationalFor the treatment of relapsed CLL, it is currently indicated as a second-line agent in combination with rituximab in patients for whom rituximab alone would be considered appropriate therapy due to other … The PI-3Ks are a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer
Lixisenatide
go.drugbank.com/drugs/DB09265ApprovedInvestigationalIt is sold by Sanofi-Aventis under the brand name Adlyxin in the US[L763] and Lyxumia in the EU.[L764] Adlyxin recieved FDA approval July 28, 2016.[L763] … Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes mellitus (T2DM).
Mixtures: Suliqua Pen, Soliqua SoloStar 100units/mL+33mcg/mL solution for injection in a pre-filled penCategories: Drugs Used in DiabetesTriamcinolone
go.drugbank.com/drugs/DB00620ApprovedInvestigationalVet approved[L8255] Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain,[L8264] or first line as a topical treatment of corticosteroid responsive dermatoses. … [L8246,L8249,L8252,L8255,L8258,L8261,L8264] Triamcinolone was granted FDA approval on 3 December 1957.
Mixtures: TRILON-E CREAM, ORACORT E DENTAL PASTEProducts: VOLONIMAT SALBE N, KENALOG IN ORABASEEtonogestrel Action Pathway
smpdb.ca/view/SMP0126525Drug actionEtonogestrel binds strongly to the progesterone receptor in the mammary gland, the hypothalamus, and the pituitary.
Enzymes: Membrane-associated progesterone receptor component 1Norethisterone Action Pathway
smpdb.ca/view/SMP0126536Drug actionThis drug has the same action as endogenous progesterone but with greater potency. … acts by altering the cervical and endometrial function, as well as it inhibits the pituitary hormones, like the Follicle-stimulating hormone (FSH) and the Luteinizing hormone (LH) via binding to progesterone
Enzymes: Membrane-associated progesterone receptor component 1Levonorgestrel Action Pathway
smpdb.ca/view/SMP0125332Drug actionLevonorgestrel acts on the hypothalamic–pituitary-gonadal axis (HPG axis) where it binds to the progesterone and the androgen receptors.
Enzymes: Membrane-associated progesterone receptor component 1Norelgestromin Action Pathway
smpdb.ca/view/SMP0126539Drug actionNorelgestromin acts on the hypothalamic–pituitary–gonadal axis (HPG axis) where it binds to the progesterone receptor.
Enzymes: Membrane-associated progesterone receptor component 1Norgestrel Action Pathway
smpdb.ca/view/SMP0126522Drug actionLevonorgestrel (the active stereoisomer of norgestrel) binds the progesterone and estrogen receptors. Those receptors are found in the mammary glands, the hypothalamus, and in the pituitary gland.
Enzymes: Membrane-associated progesterone receptor component 1Drospirenone Action Pathway
smpdb.ca/view/SMP0126538Drug actionDrospirenone is a synthetic progestin commonly found in popular oral contraceptives like Yaz, Angeliq, and Loryna. This drug is also indicated to control acne, menopause-associated symptoms, and premenstrual dysphoric disorder (PMDD) whe...
Enzymes: Membrane-associated progesterone receptor component 1