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Thioproperazine
go.drugbank.com/drugs/DB01622ApprovedThioproperazine is a potent neuroleptic with antipsychotic properties. Thioproperazine has a marked cataleptic and antiapomorphine activity associated with relatively slight sedative, hypothermic and spasmolytic effects. It is virtually ...
Categories: Dopamine D2 Receptor AntagonistsPipotiazine
go.drugbank.com/drugs/DB01621ApprovedInvestigationalWithdrawnPipotiazine has actions similar to those of other phenothiazines. Among the different phenothiazine derivatives, it appears to be less sedating and to have a weak propensity for causing hypotension or potentiating the effects of CNS depr...
Categories: Dopamine D2 Receptor AntagonistsAtogepant
go.drugbank.com/drugs/DB16098ApprovedInvestigationalIt was developed by AbbVie and received FDA approval under the brand name Qulipta in September 2021. … [propranolol]), all of which can be associated with significant adverse effects.
Lorazepam
go.drugbank.com/drugs/DB00186ApprovedInvestigationalThe first historic FDA label approval is reported in 1985 by the company Mutual Pharm.[L5095] … [A957] It was developed by DJ Richards, presented and marketed initially by Wyeth Pharmaceuticals in the USA in 1977.
Products: Nu-loraz Tab 1mg, Nu-loraz Tab 2mgCertolizumab pegol
go.drugbank.com/drugs/DB08904ApprovedInvestigational[A176606] It was developed and manufactured by UCB Pharma, first FDA approved in 2008[L45018] and updated for a new indication on March 28, 2019.[L5819] … [A176585] It is formed with a humanized Fab fragment of 50 kDa, from an IgG 1 isotype, fused to a 40 kDa polyethylene glycol moiety replacing the Fc antibody region.
Belumosudil
go.drugbank.com/drugs/DB16703ApprovedInvestigational[A236644,L34759] Belumosudil was first approved by the FDA in July 2021, under the brand name Rezurock, for the treatment of chronic GVHD in patients who have tried and failed at least two prior lines … [L34754] In July 2022, Belumosudil was approved by Health Canada under the brand name RHOLISTIQ to treat the same condition in adult and pediatric patients 12 years or older.[L42925]
Reslizumab
go.drugbank.com/drugs/DB06602ApprovedInvestigationalApproved by the FDA in March 2016, reslizumab is marketed under the brand name Cinqair for intravenous injection. It is injected once every four weeks via intravenous infusion. … Cinqair is indicated as an add-on maintenance therapy for adults with severe asthma with an eosinophilic phenotype.
Sodium borate
go.drugbank.com/drugs/DB14505ApprovedMixtures: Sel De Perou, Trimo San Deodorant Vaginal JellySulindac
go.drugbank.com/drugs/DB00605ApprovedInvestigationalSulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed by Merck under the brand name Clinoril. … Sulindac is a prodrug, derived from sulfinylindene, that is converted _in vivo_ to an active sulfide compound by liver enzymes.
Products: Nu-sulindac Tab 150mg, Nu-sulindac Tab 200mgHuman cytomegalovirus immune globulin
go.drugbank.com/drugs/DB13886ApprovedInvestigationalIt contains purified immunoglobulin G (IgG) antibodies targeting cytomegalovirus (CMV)[FDA label]. … The seroprevalence of antibodies in adults ranges from 40-100 % with an inverse correlation to socioeconomic status.
Products: MEGALOTECT CP SOLUTION FOR INFUSION 100 U/ML