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Gluconic Acid
go.drugbank.com/drugs/DB13180ApprovedInvestigationalCommonly found in salts with sodium and calcium. Gluconic acid or gluconate is used to maintain the cation-anion balance on electrolyte solutions.
Synonyms: D-Gluconic AcidMixtures: Plasma-Lyte A, INYECCION MULTIPLE DE ELECTROLITOS TIPO ITofisopam
go.drugbank.com/drugs/DB08811InvestigationalAlthough Tofisopam is not approved for sale in North America, it is approved for use in various countries worldwide, including parts of Europe. … Tofisopam (marketed under brand names Emandaxin and Grandaxin) is a 2,3-benzodiazepine drug which is a benzodiazepine derivative.
Cytisine
go.drugbank.com/drugs/DB09028InvestigationalAlso known as baptitoxine or sophorine, cytisine has been used as a smoking cessation treatment since 1964, and is relatively unknown in regions outside of central and Eastern Europe. … Cytisine is a partial nicotinic acetylcholine agonist with a half-life of 4.8 hours.
Octisalate
go.drugbank.com/drugs/DB11062ApprovedOctyl salicylate is used to augment the UVB protection in a sunscreen. Salicylates are weak UVB absorbers and they are generally used in combination with other UV filters. … Octyl salicylate appears to have a good safety profile. It covers wavelength in the range 295-315 nm, peak at 307-310 nm. It is an ester of salicylic acid and 2-ethylhexanol.
Mixtures: A M Stimulus Complex SPF 25, Cellular Day Defense Firming Complex SPF 15Categories: Compounds used in a research, industrial, or household settingGrazoprevir
go.drugbank.com/drugs/DB11575ApprovedGrazoprevir is an inhibitor of NS3/4A, a serine protease enzyme, encoded by HCV genotypes 1 and 4 [synthesis]. … in the NS5A protein and previous treatment failure with [DB00811], [DB00008], [DB00022], or other NS3/4A inhibitors like [DB08873], [DB06290], or [DB05521] [FDA Label].
Categories: NS3/4A Protease Inhibitors, HCV NS3/4A Protease InhibitorsTozinameran
go.drugbank.com/drugs/DB15696ApprovedInvestigationalFDA on July 13, 2020. … [L15027] On December 11, 2020, the FDA issued an Emergency Use Authorization (EUA) based on 95% efficacy in clinical trials and a similar safety profile to other viral vaccines over a span of approximately
Mixtures: Comirnaty Original & Omicron Ba.4/ba.5, Comirnaty Original & Omicron Ba.4/ba.5Categories: Complex MixturesTrametinib
go.drugbank.com/drugs/DB08911ApprovedInvestigational[A258298] It was later approved by Health Canada on July 18, 2013 [L45588] and by the European Commission on June 30, 2014. … [L45583] Trametinib is currently approved to treat a variety of cancers with BRAF mutations, such as non-small cell lung cancer and thyroid cancer, as monotherapy or in combination with [dabrafenib], a
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexValaciclovir
go.drugbank.com/drugs/DB00577ApprovedInvestigationalIt was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline [L5671]. Valacyclovir is the L-valine ester of aciclovir. … Genital herpes is a frequently diagnosed sexually transmitted disease which currently affects more than 400 million individuals worldwide.
Categories: Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor, Herpes Zoster Virus Nucleoside Analog DNA Polymerase InhibitorTalniflumate
go.drugbank.com/drugs/DB09295InvestigationalTalniflumate has been approved for approximately 20 years in Argentina other countries (excluding the United States, Europe, and Japan) [L1405]. … Talniflumate, is an anti-inflammatory molecule studied and used as a mucin regulator in the treatment of cystic fibrosis, chronic obstructive pulmonary disease (COPD) and asthma [L1400].
Riltozinameran
go.drugbank.com/drugs/DB17095ApprovedInvestigationalBA.4, BA.5) which, although similar, may behave differently from one another.[L43917] Riltozinameran is an mRNA vaccine encoding the S glycoprotein of SARS-CoV-2 Omicron variant lineage BA.1. … The Omicron variant of SARS-CoV-2 is a variant of concern that was first reported in November 2021.
Mixtures: Comirnaty Original/omicron Ba.1