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Darifenacin
go.drugbank.com/drugs/DB00496ApprovedInvestigationalDarifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence. Darifenacin blocks M3 muscarinic acetylcholine receptors, which mediate bladder muscle contractions.
Synonyms: (S)-1-(2-(2,3-dihydro-5-benzofuranyl)ethyl)-α,α-diphenyl-3-pyrrolidineacetamideCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsOxycodone
go.drugbank.com/drugs/DB00497ApprovedIllicitInvestigationalOxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917.
Synonyms: 4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one, 4,5α-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-oneMixtures: OXYCODON COMP 1A 5/2.5MG, OXYCODON COMP 1A 5/2.5MGTriflupromazine
go.drugbank.com/drugs/DB00508ApprovedVet approvedA phenothiazine used as an antipsychotic agent and as an antiemetic.
Synonyms: 10-(3-(Dimethylamino)propyl)-2-(trifluoromethyl)phenothiazine, 2-(Trifluoromethyl)promazineCategories: P-glycoprotein inhibitors, Heterocyclic Compounds, 3-RingEtilefrine
go.drugbank.com/drugs/DB08985ApprovedWithdrawnEtilefrine is an adrenergic agonist that appears to interact with beta-1 and some alpha-adrenergic receptors. It has been used as a vasoconstrictor agent.
Categories: Adrenergic beta-1 Receptor Agonists, Compounds used in a research, industrial, or household settingProducts: EFFORTIL® AMPOLLAS, EFFORTIL LOESUNG Z TROPFENEperisone
go.drugbank.com/drugs/DB08992InvestigationalEperisone is an antispasmodic drug which relaxes both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and
Synonyms: (2RS)-1-(4-ethylphenyl)-2-methyl-3-(1-piperidyl)propan-1-oneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesCloperastine
go.drugbank.com/drugs/DB09002InvestigationalCloperastine is a cough suppressant that acts on the central nervous system.
Categories: Heterocyclic Compounds, 1-RingProducts: CLOPERAX®, LEVRONC® SUSPENSIONCefaloridine
go.drugbank.com/drugs/DB09008ApprovedWithdrawnCephaloridine or cefaloridine is a first generation semisynthetic cephalosporin. It is derived from cephalosporin C and is a zwitterion at physiological pH.
Synonyms: ((6R,7R)-1-((2-CARBOXY-8-OXO-7-(2-(2-THIENYL)ACETAMIDO)-5-THIA-1-AZABICYCLO(4.2.0)OCT-2-EN-3-YL)METHYL)PYRIDINIUM HYDROXIDE, INNER SALT, (6R,7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)- 7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1- azabicyclo[4.2.0]oct-2-ene-2-carboxylateCategories: Heterocyclic Compounds, 2-RingArticaine
go.drugbank.com/drugs/DB09009ApprovedInvestigationalArticaine is a dental local anesthetic. Articaine is widely used around the world and is the most popular local anesthetic in many European countries.
Mixtures: Ultracaine D-S Injection, ARTHEEK(R) ARTICAINA AL 4% CON EPINEFRINA 1:100.000Categories: Heterocyclic Compounds, 1-RingCanrenoic acid
go.drugbank.com/drugs/DB09015ApprovedInvestigationalWithdrawnLike spironolactone, it is a prodrug, which is metabolized to canrenone in the body.
Bisacodyl
go.drugbank.com/drugs/DB09020ApprovedInvestigationalBisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation. … [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).
Synonyms: Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester)Mixtures: BEKUNIS 3 MG/5 MG KAPLI TABLET, 30 ADET, Dyrax-Q Tab