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Samuraciclib
go.drugbank.com/drugs/DB16061InvestigationalSamuraciclib is under investigation in clinical trial NCT03363893 (Modular Study to Evaluate CT7001 Alone in Cancer Patients With Advanced Malignancies).
LY-3200882
go.drugbank.com/drugs/DB16064InvestigationalLY-3200882 is under investigation in clinical trial NCT04158700 (A Study of LY3200882 and Pembrolizumab in Participants With Advanced Cancer).
Hetrombopag
go.drugbank.com/drugs/DB16184InvestigationalHetrombopag is under investigation in clinical trial NCT03976882 (Hetrombopag for the Treatment of Chemotherapy-induced Thrombocytopenia in Subjects With Malignancy.).
PF-08046052
go.drugbank.com/drugs/DB22647InvestigationalPF-08046052 is under investigation in clinical trial NCT05983133 (A Study of PF-08046052/SGN-EGFRd2 in Advanced Solid Tumors).
Fasitibant
go.drugbank.com/drugs/DB15646InvestigationalFasitibant is under investigation in clinical trial NCT02205814 (Fasitibant Intra-articular Injection in Patients With Symptomatic Osteoarthritis of the Knee).
Synonyms: -amino-4-((4-(((2,4-dichloro-3-(((2,4-dimethyl-8-quinolinyl)oxy)methyl)phenyl)sulfonyl)amino)tetrahydro-2h-pyran-4-yl)carbonyl)-n,n,n-trimethyl-.epsilon.-oxo-, (.delta.s)-Dezapelisib
go.drugbank.com/drugs/DB16137InvestigationalDezapelisib is under investigation in clinical trial NCT02456675 (INCB040093 and INCB040093 Combined With Itacitinib (INCB039110) in Relapsed/refractory Hodgkin Lymphoma).
Felezonexor
go.drugbank.com/drugs/DB21067InvestigationalFelezonexor is under investigation in clinical trial NCT02667873 (A Trial of a Novel XPO1 Inhibitor in Participants With Advanced Solid Tumors). … The usage of the INN stem '-nexor' in the name indicates that Felezonexor is a nuclear export inhibitor.
Telenzepine
go.drugbank.com/drugs/DB19508InvestigationalTelenzepine is under investigation in clinical trial NCT01155531 (Safety & Tolerability of a Combination of Antidepressant and Peptic Ulcer Drug in Overweight Healthy Subjects). … The usage of the INN stem '-zepine' in the name indicates that Telenzepine is a tricyclic compound.
Setileuton
go.drugbank.com/drugs/DB19550InvestigationalSetileuton is under investigation in clinical trial NCT00404313 (The Effect of MK0633 in Patients With Chronic Asthma (0633-007)). Setileuton has a monoisotopic molecular weight of 463.12 Da. … The usage of the INN stem '-leuton' in the name indicates that Setileuton is a 5-lipo-oxygenase inhibitor, anti-inflammatory.
Icovamenib
go.drugbank.com/drugs/DB21669InvestigationalIcovamenib is under investigation in clinical trial NCT06152042 (Phase 2 Trial of BMF-219 in Participants With Type 1 Diabetes Mellitus). Icovamenib has a monoisotopic molecular weight of 566.28 Da. … The usage of the INN stem '-menib' in the name indicates that Icovamenib is a menin interaction inhibitor.