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Displaying results 731 - 740 of 6198 in total
  1. Drug

    Sirolimus

    go.drugbank.com/drugs/DB00877
    ApprovedInvestigational

    [A242372] The topical formulation of sirolimus, marketed as HYFTOR, was approved by the FDA in April 2022: this marks the first topical treatment approved in the US for facial angiofibroma associated with … [A242372] In November 2000, the drug was recognized by the European Agency as an alternative to calcineurin antagonists for maintenance therapy with corticosteroids.

  2. Drug

    Norgestimate

    go.drugbank.com/drugs/DB00957
    ApprovedInvestigational

    [A191068] It was developed by Ortho Pharmaceutical Corporation as part of an effort to develop new hormonal contraceptives with reduced adverse effects. … [A191068] It is commonly formulated with [ethinylestradiol] as a combined oral contraceptive that can also be used to treat moderate acne vulgaris.

  3. Drug

    Magnesium chloride

    go.drugbank.com/drugs/DB09407
    ApprovedInvestigational

    Magnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.

    Mixtures: K+36.8, Delflex Perit.dial.soL.1.5%dex.low Ca Low mg
  4. Drug

    Valaciclovir

    go.drugbank.com/drugs/DB00577
    ApprovedInvestigational

    It was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline [L5671]. Valacyclovir is the L-valine ester of aciclovir. … It is caused by infection with the herpes simplex virus (HSV). Infection with this virus is lifelong with periodic episodes of reactivation [A175903].

    Products: Van-valacyclovir
  5. Drug

    Flosequinan

    go.drugbank.com/drugs/DB13228
    ApprovedWithdrawn

    Flosequinan was approved in the USA and the UK for a year prior to being withdrawn from the market due to increased mortality in chronic heart failure patients, found in drug trials.[A174979,L43942]

  6. Indication

    Community Acquired Pneumonia (CAP) caused by Escherichia Coli Infection

    go.drugbank.com/conditions/DBCOND0165526
    Drugs: Ceftobiprole medocaril
    Synonyms: Community Acquired Pneumonia (CAP) caused by Escherichia Coli Infection
  7. Indication

    Community Acquired Pneumonia (CAP) caused by Klebsiella Pneumoniae Infection

    go.drugbank.com/conditions/DBCOND0165527
    Drugs: Ceftobiprole medocaril
    Synonyms: Community Acquired Pneumonia (CAP) caused by Klebsiella Pneumoniae Infection
  8. Indication

    Community Acquired Pneumonia (CAP) caused by Streptococcus Pneumoniae Infections

    go.drugbank.com/conditions/DBCOND0165525
    Drugs: Ceftobiprole medocaril
    Synonyms: Community Acquired Pneumonia (CAP) caused by Streptococcus Pneumoniae Infections
  9. Drug

    Trametinib

    go.drugbank.com/drugs/DB08911
    ApprovedInvestigational

    Originally developed by Japan Tobacco, trametinib was initially investigated for treating inflammation, but further studies for this indication were not pursued.[A258298] … Trametinib is an orally bioavailable mitogen-activated extracellular signal-regulated kinase 1 (MEK1) and MEK2 inhibitor.

  10. Drug

    Chondroitin sulfate

    go.drugbank.com/drugs/DB09301
    ApprovedInvestigationalNutraceutical

    [A32063] Chondroitin sulfate is sold as an OTC dietary supplement in North America and it is a prescription drug under the EMA in Europe.[A32066]

    Mixtures: Gluco-con capsules, GLUCOSAMINA CON CONDROITINA 500/400 MG CAPSULA