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Acarbose
go.drugbank.com/drugs/DB00284ApprovedInvestigationalAcarbose is a complex oligosaccharide that acts as an inhibitor of several enzymes responsible for the breakdown of complex carbohydrates in the intestines. … [L31668] This class of antidiabetic therapy is not widely used due to their relatively modest impact on A1c, their requirement for thrice-daily dosing, and the potential for significant gastrointestinal
Products: GLUCOBAY 100 TABLET 100 mg, ACARBOSA 100 MGBelimumab
go.drugbank.com/drugs/DB08879ApprovedInvestigationalBelimumab is a fully human recombinant IgG1λ monoclonal antibody that inhibits soluble human B lymphocyte stimulator protein (BLyS, also referred to as BAFF and TNFSF13B), a B cell survival factor. … [L42630] Belimumab was first approved by the FDA on March 9, 2011,[A251495] making it the newest drug to be approved for the treatment of SLE in more than 50 years.
Products: BENLYSTA 120 MG POLVO LIOFILIZADO CONCENTRADO PARA SOLUCION PARA INFUSION, BENLYSTA 120 MG IV INFUZYONLUK COZELTI HAZIRLAMAK ICIN TOZ ICEREN FLAKON, 1 ADETFlumazenil
go.drugbank.com/drugs/DB01205ApprovedInvestigationalFumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine
Categories: Compounds used in a research, industrial, or household settingProducts: FLUMAZENIL-BAXTER SOLUTION FOR INJECTION 1 MG/10 ML, ANTİZEPİN 1 MG/10 ML İ.V. ENJEKSİYONLUK ÇÖZELTİ, 5 ADETHydrogen peroxide
go.drugbank.com/drugs/DB11091ApprovedInvestigationalVet approvedDue to its potent and broad-spectrum antimicrobial actions, hydrogen peroxide is used in both liquid and gas form for preservative, disinfection and sterilization applications as an oxidative biocide [ … Hydrogen peroxide is also considered as a generally recognized as safe compound by the FDA [L2024]; it is used as an antimicrobial agent in starch and cheese products, and as an oxidizing and reducing
Mixtures: Defense AG Disinfectant, Defense AG DisinfectantCategories: Compounds used in a research, industrial, or household settingTofacitinib
go.drugbank.com/drugs/DB08895ApprovedInvestigationalTofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and immune cell function. … Known adverse effects include nausea and headache as well as more serious immunologic and hematological adverse effects. Tofacitinib is marketed under the brand name Xeljanz by Pfizer.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Tositin 10 mg Film Kaplı Tablet, 56 ADET, XELJANZ® XR 11 MG TABLETAS DE LIBERACIÓN MODIFICADASatralizumab
go.drugbank.com/drugs/DB15762ApprovedInvestigationalan IgG2 framework. … occurs in a pH-dependent manner[A218551] - this allows satralizumab to bind an IL-6 receptor until it reaches an endosome, after which the drug may dissociate from the receptor and move back into the
Products: ENSPRYNG 120 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET, ENSPRYNG 120 mg/1ml solution for injection in pre-filled syringeCamphor
go.drugbank.com/drugs/DB01744ApprovedInvestigationalWithdrawnCamphor is a bicyclic monoterpene ketone found widely in plants, especially _Cinnamomum camphora_. It is used topically as a skin antipruritic and as an anti-infective agent. … [A254252,L43942] However, camphor can be found in several nonprescription medications at lower concentrations.[A254252]
Synonyms: D-Camphor, Camphor(D)Mixtures: Pommade Au The Des Bois, Au Kah Chuen Skin LotionSelenious acid
go.drugbank.com/drugs/DB11127ApprovedSelenium is a component of glutathione peroxidase enzyme, which protects cell components from oxidative damage due to peroxides produced during cellular metabolism [L1916]. … Selenious acid is the acid form of sodium selenite, a form of selenium [L1910]. Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation.
Mixtures: TRACUTIL® 10 ML AMPOLLASProducts: Cefasel 100 µg - Tabletten, Selenase 100 Mikrogramm/2 ml - Lösung zum EinnehmenLanreotide
go.drugbank.com/drugs/DB06791ApprovedInvestigationalThis drug is a long-acting analog of the drug somatostatin, a growth hormone inhibitor. … Lanreotide is manufactured by the company, _Ipsen Pharmaceuticals_ as lanreotide acetate, and marketed as _Somatuline_.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: Somatuline Autogel Prolonged Release Solution for Injection in a Pre-filled Syringe 120 mg, Mytolac 120 mg Injektionslösung in einer FertigspritzeDorzolamide
go.drugbank.com/drugs/DB00869ApprovedInvestigational[A1304] First marketed in 1995,[A190624] dorzolamide is available in ophthalmic solutions as monotherapy marketed as Trusopt [L11377] or in combination with [timolol] as Cosopt PF.[L11380] … [L11377] It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes.
Mixtures: Vizidor Duo 20 mg/ml + 5 mg/ml Augentropfen, NEFRIDAXEM B+DCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Substrates