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Eszopiclone
go.drugbank.com/drugs/DB00402ApprovedInvestigational[A179638,L6850] Cyclopyrrolone drugs demonstrate high efficacy and low toxicity[A179827], offering a safer alternative to other drugs used for insomnia. … Eszopiclone, marketed by Sepracor under the brand-name Lunesta, is a nonbenzodiazepine hypnotic drug used to treat insomnia.
Categories: Hypnotics and Sedatives, Zopiclone and prodrugsProducts: LUNAX 1MG, BONSONO® 2MGIrinotecan
go.drugbank.com/drugs/DB00762ApprovedInvestigational[A263376] Approved by the FDA in 1996,[A263366] irinotecan is used to treat colorectal cancer and pancreatic adenocarcinoma. … Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking its enzymatic activity, thereby interfering with DNA synthesis.
Categories: Antineoplastic and Immunomodulating AgentsProducts: TARCKORIN ® 100MG, Brinotec injection 20mg/mlMagnesium citrate
go.drugbank.com/drugs/DB11110ApprovedInvestigational[T215] Magnesium citrate is considered by the FDA as an approved inactive ingredient for approved drug products under the specifications of oral administration of a maximum concentration of 237 mg. … Magnesium citrate is a low volume and osmotic cathartic agent.
Mixtures: Calcium and Magnesium Citrate and Vitamin D 250mg/125mg/200iu, Calcium and Magnesium Citrate With Vitamin DCategories: Blood and Blood Forming Organs, Alimentary Tract and MetabolismCarboplatin
go.drugbank.com/drugs/DB00958ApprovedInvestigational[A230523] Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.[L32248] … Carboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma.[L32253] Early clinical studies of carboplatin were performed in 1982.
Categories: Indicators and Reagents, Antineoplastic and Immunomodulating AgentsProducts: Neoplatin Inj 10mg/ml, Paraplatin-AQ Inj 10mg/mlFlubendazole
go.drugbank.com/drugs/DB08974ApprovedInvestigationalWithdrawnFlubendazole is an anthelmintic that is used to treat worm infection in humans. It is available OTC in Europe.
Categories: Antiparasitic Products, Insecticides and RepellentsProducts: FLUVERMAL SUSPENSION 20MG/ML, HELMIN EX SUSPENSION 100MG/5MLGlibornuride
go.drugbank.com/drugs/DB08962ApprovedWithdrawnGlibornuride is a sulfonylurea-type anti-diabetic drug.
Categories: Alimentary Tract and MetabolismProducts: GLUTRIL 25MG TABLET, 100 ADET, GLUTRIL 25MG TABLET, 50 ADETHuman immunoglobulin G
go.drugbank.com/drugs/DB00028ApprovedInvestigationalIVIg is used in the treatment of immunodeficiencies, as well as autoimmune and inflammatory disorders. … IgG subclasses are fully represented in the following proportions: 70.3% IgG1, 24.7% IgG2, 3.1% IgG3, and 1.9% IgG4.
Categories: Amino Acids, Peptides, and ProteinsProducts: PRIVIGEN® 10% (2.5 G/25ML), HIZENTRA® 2G/ 10MLMontelukast
go.drugbank.com/drugs/DB00471ApprovedInvestigationalMontelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. … worldwide via millions of prescriptions annually and has since become available as a generic and as a brand name product.
Mixtures: BROCRIPTIN® 5MG/2.5MGCategories: Hormones, Hormone Substitutes, and Hormone Antagonists, Agents to Treat Airway DiseaseSertraline
go.drugbank.com/drugs/DB01104ApprovedInvestigationalSertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as [Citalopram] and [Fluoxetine]. … Sertraline displays enhanced safety or tolerability than other classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and other undesirable effects.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: (1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenaminePrasugrel
go.drugbank.com/drugs/DB06209ApprovedInvestigationalPrasugrel was developed by Daiichi Sankyo Co. and is currently marketed in the United States and Canada in cooperation with Eli Lilly and Company for acute coronary syndromes planned for percutaneous coronary … Prasugrel, a thienopyridine derivative, is a platelet activation and aggregation inhibitor structurally and pharmacologically related to clopidogrel and ticlopidine.
Categories: Blood and Blood Forming OrgansProducts: EFIENT 10MG, EFIENT 10MG FTA