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Displaying results 7411 - 7420 of 10000 in total
  1. Drug

    Epofolate

    go.drugbank.com/drugs/DB12266
    Investigational

    Epofolate (BMS-753493) is a folate conjugate of the epothilone analog BMS-748285 that was designed to selectively target folate receptor expressing cancer cells. … In Phase I/IIa pharmacokinetic and safety studies epofolate was generally tolerable and toxicities known to be associated with epothilone class of anticancer agents were common, although peripheral neuropathy

    Categories: Cytochrome P-450 CYP3A Inhibitors, Heterocyclic Compounds, 2-Ring
  2. Drug

    Aducanumab

    go.drugbank.com/drugs/DB12274
    ApprovedInvestigational

    [A235668,A235730] Aducanumab is a recombinant antibody derived from patients with slow or absent cognitive decline, and phase 1b clinical trial data have shown patients treated with aducanumab show a reduction … Aducanumab, or BIIB037, is a monoclonal IgG1 antibody that targets extracellular amyloid-β plaques in the brain; similar to [gantenerumab], [bapineuzumab] and [solanezumab].

  3. Drug

    Polihexanide

    go.drugbank.com/drugs/DB12277
    ApprovedInvestigational

    [A1351] It is effective against a wide range of Gram-positive and Gram-negative bacteria. … Polihexanide, also known as polyhexamethylene biguanide (PHMB), is a broad-spectrum antimicrobial polymer primarily used for topical antisepsis and wound management.

    Mixtures: Ucheer CCategories: Compounds used in a research, industrial, or household setting
  4. Drug

    AZD-5423

    go.drugbank.com/drugs/DB12280
    Investigational

    AZD5423 has been used in trials studying the basic science and treatment of Asthma, Bioavailability and AUC, and Chronic Obstructive Pulmonary Disease (COPD).

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  5. Drug

    5-Hydroxymethylfurfural

    go.drugbank.com/drugs/DB12298
    Investigational

    Aes-103 has been used in trials studying the treatment and prevention of Hypoxia, Anemia, Sickle Cell, and Sickle Cell Disease.

    Synonyms: 5-(hydroxymethyl)-2-furaldehyde, 5-(Hydroxymethyl)-2-furfuralCategories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Bavisant

    go.drugbank.com/drugs/DB12299
    Investigational

    Bavisant has been used in trials studying the basic science and treatment of Alcoholism, Pharmacokinetics, Drug Interactions, Attention Deficit Hyperactivity Disorder, and Attention Deficit Disorders With Hyperactivity.

    Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    Radotinib

    go.drugbank.com/drugs/DB12323
    Investigational

    Radotinib is under investigation for the treatment of Leukemia, Myelogenous, Chronic, BCR-ABL Positive.

    Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Aticaprant

    go.drugbank.com/drugs/DB12341
    Investigational

    Aticaprant has been used in trials studying the health services research and basic science of Anxiety Disorders and Alcohol Dependence.

    Synonyms: BENZAMIDE, 4-(4-(((2S)-2-(3,5-DIMETHYLPHENYL)-1-PYRROLIDINYL)METHYL)PHENOXY)-3-FLUORO-Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Bizelesin

    go.drugbank.com/drugs/DB12352
    Investigational

    Bizelesin has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-Ring
  10. Drug

    Ulodesine

    go.drugbank.com/drugs/DB12353
    Investigational

    Ulodesine has been used in trials studying the treatment of Gout, Arthritis, Hyperuricemia, and Joint Disease.

    Synonyms: 4H-PYRROLO(3,2-D)PYRIMIDIN-4-ONE, 1,5-DIHYDRO-7-(((3R,4R)-3-HYDROXY-4-(HYDROXYMETHYL)-1-PYRROLIDINYL)METHYL)-, 7-(((3R,4R)-3-HYDROXY-4-(HYDROXYMETHYL)PYRROLIDIN-1-YL)METHYL(-1,5-DIHYDRO-4H-PYRROLO(3,2-D)PYRIMIDIN-4-ONECategories: Heterocyclic Compounds, 1-Ring