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Displaying results 7441 - 7450 of 10000 in total
  1. Drug

    Acefylline clofibrol

    go.drugbank.com/drugs/DB21353
    Experimental

    The usage of the INN stem '-fylline' in the name indicates that Acefylline clofibrol is a N-methylated xanthine derivative. Acefylline clofibrol has a monoisotopic molecular weight of 420.12 Da.

  2. Drug

    Sofnobrutinib

    go.drugbank.com/drugs/DB21626
    Experimental

    Sofnobrutinib has a monoisotopic molecular weight of 498.19 Da. … The usage of the INN stem '-brutinib' in the name indicates that Sofnobrutinib is a agammaglobulinaemia tyrosine kinase (Bruton tyrosine kinase) inhibitor.

  3. Drug

    Lacutoclax

    go.drugbank.com/drugs/DB21657
    Investigational

    The usage of the INN stem '-toclax' in the name indicates that Lacutoclax is a B-cell lymphoma 2 (Bcl-2) inhibitor. Lacutoclax has a monoisotopic molecular weight of 922.36 Da.

  4. Drug

    Vilzemetkib

    go.drugbank.com/drugs/DB21704
    Experimental

    Vilzemetkib has a monoisotopic molecular weight of 642.27 Da. … The usage of the INN stem '-metkib' in the name indicates that Vilzemetkib is a MET (mesenchymal epithelial transition factor) kinase inhibitor.

  5. Drug

    AT-GTX-502

    go.drugbank.com/drugs/DB17001
    Experimental

    AT-GTX-502 is an experimental, one-time gene therapy that uses AAV9 to deliver a functional copy of CLN3.

    Categories: Non-Replicating Recombinant, Self-Complementary Adeno-Associated Virus Serotype 9 Containing the Human CLN3 Gene
  6. Drug

    Tunodafil

    go.drugbank.com/drugs/DB21576
    Investigational

    Tunodafil is under investigation in clinical trial NCT05976503 (A Study of the Interaction of Tunodafil Hydrochloride Tablets and Alcohol). Tunodafil has a monoisotopic molecular weight of 487.23 Da. … The usage of the INN stem '-afil' in the name indicates that Tunodafil is a inhibitor of phosphodiesterase PDE5 with vasodilator action.

  7. Drug

    LI-301

    go.drugbank.com/drugs/DB05509
    Experimental

    It has a novel mode of action combining both the light effect of a Selective Serotonin Reuptake Inhibitor ("SSRI")(most likely antagonistic at 5HT1a receptors) and antagonism at mu-opioid receptors. … This results in a slight dulling of sensation that can be used to treat premature ejaculation without interfering with normal sexual pleasure or orgasm.

  8. Drug

    Chromic nitrate

    go.drugbank.com/drugs/DB14527
    Approved

  9. Drug

    Utatrectinib

    go.drugbank.com/drugs/DB21295
    Investigational

    Utatrectinib is under investigation in clinical trial NCT01468324 (AZD7451 for Recurrent Gliomas). Utatrectinib has a monoisotopic molecular weight of 382.17 Da. … The usage of the INN stem '-trectinib' in the name indicates that Utatrectinib is a tropomyosin receptor kinase (TRK) inhibitor.

  10. Drug

    Trastuzumab botidotin

    go.drugbank.com/drugs/DB17413
    Experimental

    A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable