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Displaying results 741 - 750 of 8970 in total
  1. Drug

    Dactinomycin

    go.drugbank.com/drugs/DB00970
    ApprovedInvestigational

    It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. … A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus.

    Products: DACTINOMYCIN FOR INJECTION 0.5 mg/vial
  2. Drug

    Protein C

    go.drugbank.com/drugs/DB11312
    ApprovedInvestigational

    It is converted by the thrombin/thrombomodulin-complex on the endothelial cell surface to Activated Protein C (APC). … The Protein C pathway provides a natural mechanism for control of the coagulation system and prevention of excessive procoagulant responses to activating stimuli.

    Mixtures: OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU, BERIPLEX P/N 500 POWDER FOR SOLUTION FOR INJECTIONProducts: CEPROTIN 500 IU IV ENJEKSİYONLUK ÇÖZELTİ İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON
  3. Drug

    Levofloxacin

    go.drugbank.com/drugs/DB01137
    ApprovedInvestigational

    (i.e. it does not invert to the inactive isomer). … [A190663] It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin[A190663] and remains stereochemically stable following administration

    Synonyms: Ofloxacin S-(-)-formCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  4. Drug

    Edaravone

    go.drugbank.com/drugs/DB12243
    ApprovedInvestigational

    by the Committee for Medicinal Products for Human Use (CHMP) for a long-term study demonstrating the long-term efficacy and safety of edaravone. … However, the drug manufacturer, Mitsubishi Tanabe Pharma, withdrew the Marketing Authorization Application (MAA) for edaravone from the European market on May 24, 2019, in response to the request made

    Categories: Compounds used in a research, industrial, or household settingProducts: RADICAVA™ IV Concentrate Solution for Infusion 30mg/20mL
  5. Drug

    Varicella zoster vaccine (live/attenuated)

    go.drugbank.com/drugs/DB10318
    ApprovedInvestigational

    While the two vaccines contain the same immunological components and provide protection against the same virus, Zostavax contains a higher dose and is used in older adults to prevent the development of … First approved in May 2006 by the Food and Drug Administration, Zostavax was the first vaccine available for the prevention of shingles.

    Mixtures: PROQUAD 0.5 ML ENJEKSIYONLUK SÜSPANSIYON HAZIRLAMAK IÇIN LIYOFILIZE TOZ IÇEREN FLAKON VE ÇÖZÜCÜ IÇEREN ENJEKTÖR , 1 ADET, PRIORIX-TETRA 0.5 ML SC ENJEKSIYON IÇIN LIYOFILIZE TOZ IÇEREN FLAKON VE ÇÖZÜCÜ IÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 DOZ İĞNELİCategories: Antiinfectives for Systemic Use
  6. Drug

    Metronidazole

    go.drugbank.com/drugs/DB00916
    ApprovedInvestigational

    [A181036,A181039] Metronidazole has been used as an antibiotic for several decades[L7429], with added antiparasitic properties that set it apart from many other antibacterial drugs, allowing it to treat … It is available in capsule form, tablet form, and topical form, and suppository preparations for the treatment of various infections.

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: METRONIDAZOLO SAME, FLAGYL INJECTION FOR INTRAVENOUS INFUSION 0.5% w/v
  7. Drug

    Cisatracurium

    go.drugbank.com/drugs/DB00565
    ApprovedInvestigational

    Cisatracurium is a non-depolarising neuromuscular blocking agent of the benzylisoquinolinium class, available in its salt form, cisatracurium besylate. … [A243416] Compared to atracurium, cisatracurium produces a lower degree of histamine release.[A253597]

    Products: Cisatracurium Kabi 2 mg/ml solution for injection or infusion, Atrax Inj Cisatracurium Besylate Injection, USP Solution for Injection or Infusion 2 mg/ml
  8. Drug

    Fomepizole

    go.drugbank.com/drugs/DB01213
    ApprovedVet approved

    Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites. … Fomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning.

    Categories: Compounds used in a research, industrial, or household settingProducts: Fomepizole for Injection
  9. Drug

    Cocoa butter

    go.drugbank.com/drugs/DB11086
    Approved

    Still, it is a common active ingredient for prevention of skin dryness in cosmetic and skincare products. … It is a rich source of monounsaturated and saturated fatty acids [A33040] that mainly contains approximately 33% [DB04224], 25% [DB03796], and 33% [DB03193] [A20409] but does not contain caffeine or theobromine

    Products: Dermatitica Synergy for treatment of Dermatitis
  10. Drug

    Chloroxylenol

    go.drugbank.com/drugs/DB11121
    Approved

    The halophenol is shown to be most effective against Gram positive bacteria where it disrupts the cell wall due to its phenolic nature [A1351]. … Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments.

    Mixtures: FOILLE SOLE, FOILLE SOLECategories: Compounds used in a research, industrial, or household setting