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Lebrikizumab
go.drugbank.com/drugs/DB11914ApprovedInvestigationalLebrikizumab is a monoclonal antibody that binds to IL-13 with high affinity and slow off-rate.[L51374] It binds to a different epitope compared [tralokinumab]. … November 17, 2023, lebrikizumab was approved by the EMA under the brand name EBGLYSS for the treatment of moderate-to-severe atopic dermatitis in adult and adolescent patients 12 years and older with a
Guadecitabine
go.drugbank.com/drugs/DB11918InvestigationalGuadecitabine is under investigation for the treatment of Previously Treated Metastatic Colorectal Cancer.
Categories: Heterocyclic Compounds, 1-Ring6-O-benzylguanine
go.drugbank.com/drugs/DB11919Investigational6-O-benzylguanine has been used in trials studying the treatment of HIV Infection, Adult Gliosarcoma, Adult Glioblastoma, Stage I Adult Hodgkin Lymphoma, and Stage II Adult Hodgkin Lymphoma, among others
Synonyms: O(6)-BenzylguanineCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesLesogaberan
go.drugbank.com/drugs/DB11920InvestigationalLesogaberan has been used in trials studying the treatment and basic science of GERD, Reflux, Heartburn, Regurgitation, and Reflux Disease, among others.
Categories: GABA-A Receptor AgonistsEpelsiban
go.drugbank.com/drugs/DB11934InvestigationalEpelsiban has been investigated for the treatment of Premature Ejaculation.
Categories: Heterocyclic Compounds, 1-RingFlomoxef
go.drugbank.com/drugs/DB11935InvestigationalFlomoxef has been used in trials studying the treatment of Urinary Tract Infection.
Categories: Heterocyclic Compounds, 2-RingTriapine
go.drugbank.com/drugs/DB11940InvestigationalTriapine has been used in trials studying the treatment of Leukemia, Lung Cancer, Kidney Cancer, Prostate Cancer, and Pancreatic Cancer, among others.
Synonyms: 3-Aminopyridine-2-carboxaldehyde thiosemicarbazoneCategories: Heterocyclic Compounds, 1-RingTeneligliptin
go.drugbank.com/drugs/DB11950InvestigationalTeneligliptin has been investigated for the treatment of Type 2 Diabetes Mellitus.
Categories: Heterocyclic Compounds, 1-RingIdalopirdine
go.drugbank.com/drugs/DB11957InvestigationalIdalopirdine has been used in trials studying the treatment of Cognition, Schizophrenia, and Alzheimer's Disease.
Categories: Heterocyclic Compounds, 2-RingAZD-1236
go.drugbank.com/drugs/DB11961InvestigationalAZD1236 has been used in trials studying the basic science and treatment of Cystic Fibrosis and Chronic Obstructive Pulmonary Disease.
Categories: Heterocyclic Compounds, 1-Ring