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Displaying results 7561 - 7570 of 10000 in total
  1. Drug

    Pemlimogene merolisbac

    go.drugbank.com/drugs/DB16286
    Investigational

    Pemlimogene merolisbac is under investigation in clinical trial NCT03371381 (An Efficacy and Safety Study of JNJ-64041757, a Live Attenuated Listeria Monocytogenes Immunotherapy, in Combination With Nivolumab … Versus Nivolumab Monotherapy in Participants With Advanced Adenocarcinoma of the Lung).

    Synonyms: Recombinant live-attenuated double-deleted (ladd) strain of listeria monocytogenes (lm .delta.acta/.delta.inlb) expressing a fusion protein comprising the n-terminal 100 amino acids of the lm acta protein, (actan100), 5 tandem copies of a 21 amino acid fr
  2. Drug

    Exbivirumab

    go.drugbank.com/drugs/DB17747
    Experimental

    It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies to the hepatitis B virus (HBV) surface antigen.[A259202] … Exbivirumab is an investigational monoclonal antibody.

    Synonyms: Immunoglobulin g, anti-(hepatitis b surface antigen) (human monoclonal 19.79.5 heavy chain), disulfide with human monoclonal 19.79.5 .lambda. chain, dimer
  3. Drug

    Talabostat

    go.drugbank.com/drugs/DB06182
    Investigational

  4. Drug

    Neopterin

    go.drugbank.com/drugs/DB15050
    Investigational

    Neopterin is under investigation in clinical trial NCT02974192 (Neopterin Effects on Ischemic Stroke).

    Categories: Heterocyclic Compounds, 2-Ring
  5. Drug

    Oxatomide

    go.drugbank.com/drugs/DB12877
    Approved

    Oxatomide has been used in trials studying the treatment of Muscular Dystrophy, Duchenne.

    Categories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Parthenolide

    go.drugbank.com/drugs/DB13063
    ApprovedInvestigational

    Parthenolide has been used in trials studying the diagnostic of Allergic Contact Dermatitis.

  7. Drug

    Elbimilast

    go.drugbank.com/drugs/DB20663
    Investigational

    Elbimilast is a small molecule drug. The usage of the INN stem '-milast' in the name indicates that Elbimilast is a Phosphodiesterase-4 (PDE4) inhibitor. … Elbimilast is under investigation in clinical trial NCT00977886 (Safety and Pharmacokinetics of ELB353 in Healthy Men). Elbimilast has a monoisotopic molecular weight of 442.04 Da.

  8. Drug

    GC-373

    go.drugbank.com/drugs/DB15797
    Experimental

    Along with its prodrug, GC-376, GC-373 was recently investigated _in vitro_ in cell culture against SARS-Cov-2 M<sup>pro</sup> [A219036]. … It is an inhibitor of M<sup>pro</sup> (otherwise known as 3CL<sup>pro</sup>), a viral encoded protease that cleaves and activates functional proteins involved in viral replication and transcription[A219036

    Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Inosine 5'-sulfate

    go.drugbank.com/drugs/DB05973
    Experimental

  10. Drug

    Rubitecan

    go.drugbank.com/drugs/DB06159
    Investigational

    Synonyms: 1H-PYRANO(3',4':6,7)INDOLIZINO(1,2-B)QUINOLINE-3,14(4H,12H)-DIONE, 4-ETHYL-4-HYDROXY-10-NITRO-, (4S)-, 9-nitro-20(S)-camptothecinCategories: Topoisomerase I Inhibitors