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Displaying results 751 - 760 of 10000 in total
  1. Indication

    Osteogenesis Imperfecta (OI)

    go.drugbank.com/conditions/DBCOND0113457
    Drugs: Alendronic acid · Neridronic Acid
    Synonyms: Osteogenesis Imperfecta, Type I, Osteogenesis imperfecta type I
  2. Target

    Flavohemoprotein

    go.drugbank.com/bio_entities/BE0002917
    TargetEscherichia coli (strain K12)

    Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various

    Synonyms: NO oxygenase
  3. Drug

    Ipratropium

    go.drugbank.com/drugs/DB00332
    ApprovedInvestigational

    Ipratropium is a quaternary ammonium derivative of [atropine][A176957] that acts as an anticholinergic agent. … [A176957] Ipratropium as a therapeutic agent was developed by Boehringer Ingelheim and its first monotherapy product was FDA approved in 1986, while the combination product of ipratropium and [albuterol

    Mixtures: BERODUAL N METERED DOSE INHALER, BERODUAL N METERED DOSE INHALERCategories: Agents to Treat Airway Disease
  4. Indication

    Peripheral T-Cell Lymphoma (PTCL)

    go.drugbank.com/conditions/DBCOND0079798
    Drugs: Brentuximab vedotin
    Synonyms: Peripheral T-cell lymphoma, no ICD-O subtype, Peripheral T-cell lymphoma, no International Classification of Diseases for Oncology subtype
  5. Drug

    Peracetic acid

    go.drugbank.com/drugs/DB14556
    Investigational

    A liquid that functions as a strong oxidizing agent. It has an acrid odor and is used as a disinfectant.

    Categories: Compounds used in a research, industrial, or household settingProducts: Peraflu D, Pu Us Pure
  6. Drug

    Pravastatin

    go.drugbank.com/drugs/DB00175
    ApprovedInvestigational

    It was the first statin administered as the active form and not as a prodrug.[T274] This drug was developed by Sankyo Co. … The manufacturing process is followed by the hydrolysis of the lactone group and the biological hydroxylation with _Streptomyces carbophilus_ to introduce the allylic 6-alcohol group.[T239]

    Mixtures: PRAVAFEN® CAPSULASCategories: P-glycoprotein substrates
  7. Drug

    Calcitriol

    go.drugbank.com/drugs/DB00136
    ApprovedInvestigationalNutraceutical

    It is produced in the body after series of conversion steps of 7-dehydrocholesterol from exposure to UV light. 7-dehydrocholesterol is converted to [DB00169] (vitamin D3) in the skin, which is then converted … In addition to promoting fatty acid synthesis and inhibiting lipolysis, calcitriol has been demonstrated to increase energy efficiency by suppressing UCP2 expression, which is modulated by signaling pathways

    Categories: Vitamin D and Analogues, Cytochrome P-450 SubstratesSynonyms: 1-alpha-25-Dihydroxyvitamin D3
  8. Drug

    Carbidopa

    go.drugbank.com/drugs/DB00190
    ApprovedInvestigational

    An individual formulation containing solely carbidopa was generated to treat nausea in patients where the combination therapy [levodopa]/carbidopa is not efficient reducing nausea. … [L5110] On the other hand, the combination treatment of carbidopa/levodopa was originally developed by Watson Labs but the historical information by the FDA brings back to the approval of this combination

    Mixtures: LEVODO CA E P100/25/200, LEVODO CA E P100/25/200Categories: Aromatic L-amino Acid Decarboxylase Inhibitors
  9. Drug

    Magnesium lactate

    go.drugbank.com/drugs/DB14515
    InvestigationalNutraceutical

    Products: Magnesium Lactate Cap 70mg
  10. Drug

    Epidermal Growth Factor Receptor variant III (EGFRvIII) chimeric antigen receptor T cells

    go.drugbank.com/drugs/DB18654
    Investigational

    Synonyms: EGFRvIII CAR-T, Autologous Chimeric Antigen Receptor (CAR) Modified Recombinant T Cells Targeting EGFRvIII