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Entacapone
go.drugbank.com/drugs/DB00494ApprovedInvestigationalWhen administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased and more sustained plasma levodopa concentrations are reached as compared to the administration … of levodopa and a decarboxylase inhibitor.
Mixtures: LCE 1A PHARMA 100/25/200, LCE 1A PHARMA 100/25/200Cobalamin
go.drugbank.com/drugs/DB14098ApprovedInvestigationalMixtures: Vital-D Rx, Select-OB Plus DHA Prenatal Supplement Plus DHACategories: Vitamin B ComplexChlorthalidone
go.drugbank.com/drugs/DB00310ApprovedInvestigationalheart failure when compared to [DB00722], [DB00381], or [DB00590]. … These pathways may play a role in chlorthalidone's cardiovascular risk reduction effects.[A176330]
Mixtures: Aa-atenidone, Aa-atenidoneMepyramine
go.drugbank.com/drugs/DB06691ApprovedVet approvedIt is a first generation antihistamine. However, it rapidly permeates the brain and so often causes drowsiness as a side effect.
Mixtures: Zotex-D, Deconsal DMAntihemophilic factor (recombinant), PEGylated
go.drugbank.com/drugs/DB09329ApprovedInvestigationalwith at least one molecule of polyethylene glycol (MW 20 kDa) [FDA label]. … PEGylation is the covalent attachment of a polyethylene glycol polymer, called PEG, to a drug or protein.
Categories: Compounds used in a research, industrial, or household settingDavesomeran
go.drugbank.com/drugs/DB17091ApprovedInvestigationalModerna Bivalent vaccine elicit a higher seroresponse both against the original SARS-CoV-2 strain and the BA.4/5 strain compared to that of the Moderna COVID-19 Vaccine. … [L43882] A phase 2 and 3 open-label study in participants 18 years or older who had previously received a two-dose primary series and one booster dose of Moderna COVID-19 Vaccine demonstrated that the
Mixtures: Spikevax Bivalent (original / Omicron Ba.4/5)Mifamurtide
go.drugbank.com/drugs/DB13615ApprovedInvestigationalAs a liposomal formulation, mifamurtide demonstrates an enhanced tumoricidal effect and improved safety profile [A31745]. Mifamurtide is marketed in Europe as Mepact for intravenous infusion. … Also called L-MTP-PE, mifamurtide may be a liposomal form of of the active ingredient MTP-PE, which is a synthetic, less pyrogenic, and longer-acting derivative of muramyl dipeptide (MDP).
Zinc sulfate, unspecified form
go.drugbank.com/drugs/DB14548ApprovedZinc sulfate is a common zinc supplement in parenteral nutrition.[A216916,L12888]
Mixtures: Virt-C DHA, Taron-C DHASulfamethoxazole
go.drugbank.com/drugs/DB01015ApprovedInvestigationalSulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria. … [L11830] In this combination, sulfamethoxazole is useful for the treatment of a variety of bacterial infections, including those of the urinary, respiratory, and gastrointestinal tracts.
Mixtures: Bactrim DS, Bactrim DSAmitriptyline
go.drugbank.com/drugs/DB00321ApprovedInvestigationalAmitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961.
Mixtures: Limbitrol DS, Etrafon D TabCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index