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Taurolidine
go.drugbank.com/drugs/DB12473ApprovedInvestigationalTaurolidine is an antimicrobial used for the prevention of catheter-related infections. It is a derivative of the amino acid [taurine]. … It was first synthesized in the 1970s and was originally used as a prophylactic against intraperitoneal bacterial infections in patients with peritonitis.
Categories: Heterocyclic Compounds, 1-RingProducts: Taurolin (Taurolidin "Geistlich") 2% - InstillationslösungTetrahydrouridine
go.drugbank.com/drugs/DB12484InvestigationalTetrahydrouridine has been used in trials studying the treatment of Neoplasms, Lung Neoplasms, Breast Neoplasms, Sickle Cell Disease, and Head and Neck Cancer, among others.
Categories: Heterocyclic Compounds, 1-RingFasiglifam
go.drugbank.com/drugs/DB12491InvestigationalFasiglifam has been used in trials studying the treatment of Chronic Kidney Disease, Type 2 Diabetes Mellitus, and Diabetes Mellitus, Type 2.
Categories: Heterocyclic Compounds, 2-RingPiritramide
go.drugbank.com/drugs/DB12492ApprovedWithdrawnPiritramide is under investigation for the treatment of Colon Cancer and Minimal Residual Disease.
Categories: Heterocyclic Compounds, 1-RingClascoterone
go.drugbank.com/drugs/DB12499ApprovedInvestigational[L15621] Clascoterone is also being investigated as a novel treatment for androgenetic alopecia.[A218766] … Clascoterone (cortexolone 17α-propionate, CB-03-01) is a novel antagonist of androgen receptors. It binds to androgen receptors with high affinity.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2B6 InhibitorsAtecegatran metoxil
go.drugbank.com/drugs/DB12507InvestigationalAtecegatran metoxil has been used in trials studying the basic science and prevention of Nonvalvular Atrial Fibrillation, Persistent or Permanent Nonvalvular Atrial Fibrillation, and Persistent or Permanent Non-valvular Atrial Fibrillation.
Categories: Heterocyclic Compounds, 1-RingImiglitazar
go.drugbank.com/drugs/DB12511InvestigationalImiglitazar has been used in trials studying the treatment of Diabetes Mellitus.
Categories: Heterocyclic Compounds, 1-RingVerucerfont
go.drugbank.com/drugs/DB12512InvestigationalVerucerfont has been used in trials studying the treatment of Congenital Adrenal Hyperplasia.
Categories: Heterocyclic Compounds, 1-RingIofolastat I-123
go.drugbank.com/drugs/DB12514InvestigationalIofolastat I-123 is under investigation in clinical trial NCT00992745 (A Phase I Pilot Study Comparing 123I MIP 1072 Versus 111In Capromab Pendetide in Subjects With Metastatic Prostate Cancer).
Synonyms: Iofolastat i 123, Iofolastat (123 I)BI-671800
go.drugbank.com/drugs/DB12524InvestigationalBi 671800 has been used in trials studying the treatment of Asthma and Rhinitis, Allergic, Perennial.
Categories: Heterocyclic Compounds, 1-Ring