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Isometheptene
go.drugbank.com/drugs/DB06706ApprovedIsometheptene is a sympathomimetic drug that causes vasoconstriction. It is used for treating migraines and tension headaches.
Mixtures: CAFETRIN ®, ANTIALGINA®Categories: Adrenergic alpha-1 Receptor AgonistsLevonordefrin
go.drugbank.com/drugs/DB06707ApprovedInvestigationalLevonordefrin acts as a topical nasal decongestant and vasoconstrictor, most often used in dentistry.
Mixtures: Scandonest L, Scandonest 2% LSynonyms: L-Nordefrin, L-alpha-methylnoradrenalineLumefantrine
go.drugbank.com/drugs/DB06708ApprovedInvestigational</i> and may be used to treat infections caused by <i>P. falciparum</i> and unidentified <i>Plasmodium</i> species, including infections acquired in chloroquine-resistant areas. … This combination therapy exerts its effects against the erythrocytic stages of <i>Plasmodium spp.
Mixtures: KOMEFAN ® 280, ARTEMETERO Y LUMEFANTRINACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsNilvadipine
go.drugbank.com/drugs/DB06712ApprovedNilvadipine is a calcium channel blocker (CCB) for the treatment of hypertension.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: Tensan retard 8 mg - KapselnVelaglucerase alfa
go.drugbank.com/drugs/DB06720ApprovedVelaglucerase alfa is a gene-activated human recombinant glucocerebrosidase used for the treatment of Type 1 Gaucher disease, caused by a deficiency of the lysosomal enzyme glucocerebrosidase. … Additionally, Velaglucerase alfa has also been investigated for use in Type 3 Gaucher disease.
Synonyms: GA-GCBProducts: VPRIV ®, VPRIV 400 ÜNİTE İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 5 ADETAniline
go.drugbank.com/drugs/DB06728InvestigationalConsisting of an amine attached to a benzene ring, aniline is the prototypical aromatic amine. … Aniline is colorless, but it slowly oxidizes and resinifies in air, giving a red-brown tint to aged samples.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 SubstratesSynonyms: Fentanyl impurity F, Trimethoprim specified impurity KGestodene
go.drugbank.com/drugs/DB06730InvestigationalGestodene is a progestogen hormonal contraceptive.
Mixtures: FEMIANE®, FEMIANE®Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitorsbeta-Naphthoflavone
go.drugbank.com/drugs/DB06732ExperimentalIt may be a chemopreventive agent. … β-Naphthoflavone, also known as 5,6-benzoflavone, is a potent agonist of the aryl hydrocarbon receptor and induces cytochromes P450 (CYPs) and uridine 5'-diphospho-glucuronosyltransferases (UGTs).
Categories: Cytochrome P-450 CYP1A2 Inducers, Heterocyclic Compounds, 1-RingSynonyms: 3-phenyl-1H-naphtho(2,1-b)pyran-1-one, β-NFBafilomycin A1
go.drugbank.com/drugs/DB06733ExperimentalThis is a useful tool as it can prevent the re-acidification of synaptic vesicles once they have undergone exocytosis. … The bafilomycins refer to a category of toxic macrolide antibiotics that are derivatives of Streptomyces griseus.
Zaltoprofen
go.drugbank.com/drugs/DB06737InvestigationalA non-steroidal anti-inflammatory drug approved for use in Japan in 1993.
Categories: Cytochrome P-450 Substrates, Non COX-2 selective NSAIDS