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TAS-106
go.drugbank.com/drugs/DB06656InvestigationalTAS-106 is a new nucleoside antimetabolite. TAS-106 has demonstrated strong antitumor activity without serious toxicity in nude rat models bearing human tumours [A31693].
Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-Amino-1-((2R,3R,4R,5R)-4-ethynyl-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)pyrimidin-2-one, 3'-C-EthynylcytidineRostaporfin
go.drugbank.com/drugs/DB06659InvestigationalCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds with 4 or More RingsLixivaptan
go.drugbank.com/drugs/DB06666InvestigationalCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingAmediplase
go.drugbank.com/drugs/DB06679ExperimentalAmediplase is a recombinant chimeric plasminogen activator, consisting of the kringle 2 domain from the A-chain of tissue plasminogen activator (t-PA) and the carboxy terminal region of pro-urokinase.
Mevastatin
go.drugbank.com/drugs/DB06693ExperimentalMevastatin or compactin is a cholesterol-lowering agent isolated from <i>Penicillium citinium</i>. … Mevastatin is a competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase with a binding affinity 10,000 times greater than the HMG-CoA substrate itself.
Isometheptene
go.drugbank.com/drugs/DB06706ApprovedIsometheptene is a sympathomimetic drug that causes vasoconstriction. It is used for treating migraines and tension headaches.
Mixtures: CAFETRIN ®, ANTIALGINA®Categories: Adrenergic alpha-1 Receptor AgonistsLevonordefrin
go.drugbank.com/drugs/DB06707ApprovedInvestigationalLevonordefrin acts as a topical nasal decongestant and vasoconstrictor, most often used in dentistry.
Mixtures: Scandonest 2% L, Scandonest LSynonyms: L-Nordefrin, L-alpha-methylnoradrenalineLumefantrine
go.drugbank.com/drugs/DB06708ApprovedInvestigational</i> and may be used to treat infections caused by <i>P. falciparum</i> and unidentified <i>Plasmodium</i> species, including infections acquired in chloroquine-resistant areas. … This combination therapy exerts its effects against the erythrocytic stages of <i>Plasmodium spp.
Mixtures: KOMEFAN ® 280, ARTEMETERO Y LUMEFANTRINACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsNilvadipine
go.drugbank.com/drugs/DB06712ApprovedNilvadipine is a calcium channel blocker (CCB) for the treatment of hypertension.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: Tensan retard 8 mg - Kapseln