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Displaying results 761 - 770 of 10000 in total
  1. Drug

    Epidermal Growth Factor Receptor variant III (EGFRvIII) chimeric antigen receptor T cells

    go.drugbank.com/drugs/DB18654
    Investigational

    Synonyms: EGFRvIII CAR-T, Autologous Chimeric Antigen Receptor (CAR) Modified Recombinant T Cells Targeting EGFRvIII
  2. Drug

    Channel catfish

    go.drugbank.com/drugs/DB15548
    Approved

    Channel catfish allergenic extract is used in allergenic testing.

    Synonyms: Spotted cat
  3. Drug

    Filgrastim

    go.drugbank.com/drugs/DB00099
    ApprovedInvestigational

    It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in _E. Coli_. … [L40714] Filgrastim was approved in the US in 1991 and there are biosimilars available with similar therapeutic indications.[A245858] Tbo-filgrastim was approved by the FDA on August 29, 2012.

    Synonyms: r-metHuG-CSFInternational brands: White-C
  4. Drug

    Mebendazole

    go.drugbank.com/drugs/DB00643
    ApprovedInvestigationalVet approved

    A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]

    Mixtures: L-OMBRIX-DUET, L-OMBRIX-DUETCategories: Heterocyclic Compounds, 2-Ring
  5. Indication

    Chronic Granulocytic Leukemias

    go.drugbank.com/conditions/DBCOND0143005
    Drugs: Cyclophosphamide
    Synonyms: Chronic myelogenous leukemia, no ICD-O subtype, Chronic myelogenous leukemia, no ICD-O subtype (morphologic abnormality)
  6. Drug

    Rizatriptan

    go.drugbank.com/drugs/DB00953
    ApprovedInvestigational

    [L46018] Used in the treatment of migraines, rizatriptan was first approved in the US in 1998. … Rizatriptan is a second-generation triptan [A258918] and a selective 5-HT<sub>1B and 5-HT1D</sub> receptor agonist.

    Synonyms: N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]-ethanamine, N,N-Dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamineCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Heterocyclic Compounds, 1-Ring
  7. Drug

    B7-H3-specific chimeric antigen receptor T cells

    go.drugbank.com/drugs/DB18567
    Experimental

    Synonyms: allogeneic T cells genetically modified to express anti-B7-H3 chimeric antigen receptor (CAR), Autologous chimeric antigen receptor (CAR) T cells targeting B7-H3
  8. Indication

    Cutaneous T-Cell Lymphoma (CTCL)

    go.drugbank.com/conditions/DBCOND0071861
    Drugs: Cladribine · Gemcitabine · Interferon alfa-2a · Methoxsalen · Pralatrexate · Romidepsin
    Synonyms: Cutaneous T-cell lymphoma, no ICD-O subtype, Cutaneous T-cell lymphoma, no International Classification of Diseases for Oncology subtype
  9. Drug

    Codeine

    go.drugbank.com/drugs/DB00318
    ApprovedIllicitInvestigational

    Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease pain by increasing the threshold for pain without impairing consciousness or altering other sensory … The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities.

    Mixtures: Phenaphen No 3 Cap, Phenaphen No 4 CapCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 Substrates
  10. Target

    Carbonic anhydrase 1

    go.drugbank.com/bio_entities/BE0000267
    TargetEnzymeCarrierHumans

    Can hydrate cyanamide to urea (PubMed:10550681)

    Synonyms: CA-I, Carbonic anhydrase I