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Naloxegol
go.drugbank.com/drugs/DB09049ApprovedInvestigationalThe advantage of naloxegol over the opioid antagonist naloxone is that its PEGylated structure allows for high selectivity for peripheral opioid receptors and lack of entry into the central nervous system
Synonyms: (5α,6α)-17-Allyl-6-[(20-hydroxy-3,6,9,12,15,18-hexaoxaicos-1-yl)oxy]-4,5-epoxymorphinan-3,14-diolCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 InhibitorsAdakitug
go.drugbank.com/drugs/DB05484InvestigationalMDX-018, also known as HuMax-Inflam, is a fully human antibody that is directed to IL-8 (interleukin-8) and may have potential application in oncology and inflammation.
Synonyms: HuMax IL-8, HuMax-IL-8Cyproheptadine
go.drugbank.com/drugs/DB00434ApprovedInvestigationalCyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors. It is used primarily to treat allergic symptoms, though it is perhaps more notable for its use in appetite stimulation and its off-label use in ...
Products: PRAKTEN 2 MG/5 ML ŞURUP, 240 ML, PRAKTEN SURUP, 240 MLPF-04620110
go.drugbank.com/drugs/DB14887InvestigationalPF-04620110 is under investigation in clinical trial NCT01146327 (A Multiple Dose Study Of PF-04620110 In Healthy Overweight Or Obese Subjects).
Almasilate
go.drugbank.com/drugs/DB13595ApprovedAlmasilate is a buffering antacid that has been used in peptic ulcers and dyspepsia. It is a crystalline polyhydrate of aluminium/magnesium silicate and mediates its buffering activity by binding hydrogen ions within the polymer. However...
Phenoxyethanol
go.drugbank.com/drugs/DB11304ApprovedInvestigationalPhenoxyethanol (EU), or PE, is the most commonly used globally-approved preservative in personal care formulations. It is very easy to use in various types of formulations and is chemically stable.
Mixtures: OCTENISEPT ÇÖZELTI, 50 ML, OCTENISEPT ÇÖZELTI, 250 MLAmorolfine
go.drugbank.com/drugs/DB09056ApprovedWithdrawnIt is approved for sale over the counter in Australia and the UK (recently re-classified to over the counter status), and is approved for the treatment of toenail fungus by prescription in other countries
Products: RAZOLE %5 TIRNAK CILASI, 5 ML, RAZOLE %5 TIRNAK CILASI, 2.5 MLErdafitinib
go.drugbank.com/drugs/DB12147ApprovedInvestigationaltool kit to treat such a prevalent medical condition. … In early April of 2019, the US FDA approved Janssen Pharmaceutical Companies' brand name Balversa (erdafitinib) as the first-ever fibroblast growth factor receptor (FGFR) kinase inhibitor indicated for
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesGotistobart
go.drugbank.com/drugs/DB19100InvestigationalGotistobart is under investigation in clinical trial NCT05671510 (ONC-392 Versus Docetaxel in Metastatic NSCLC That Progressed on PD-1/PD-L1 Inhibitors).
Polaprezinc
go.drugbank.com/drugs/DB09221InvestigationalPolaprezinc is a chelated form of zinc and L-carnosine. It is a zinc-related medicine approved for the first time in Japan, which has been clinically used to treat gastric ulcers [L1307, L1308].
Synonyms: Zinc L-carnosine, beta-Alanyl-L-histidinato zinc