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Group 10 secretory phospholipase A2
go.drugbank.com/bio_entities/BE0000070TargetEnzymeHumansSecretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids (PubMed:12021277, PubMed:9188469). Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids with preferen...
Polypeptides: Group 10 secretory phospholipase A2Synonyms: Phosphatidylcholine 2-acylhydrolase 10Interleukin-10 receptor subunit alpha
go.drugbank.com/bio_entities/BE0014391TargetHumansCell surface receptor for the cytokine IL10 that participates in IL10-mediated anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Upon binding to IL10, induces a conformational change in IL10RB, all...
Polypeptides: Interleukin-10 receptor subunit alphaSynonyms: IL-10 receptor subunit alpha, Interleukin-10 receptor subunit 1Bcl-2-like protein 10
go.drugbank.com/bio_entities/BE0019838TargetHumansPromotes cell survival by suppressing apoptosis induced by BAX but not BAK (PubMed:11278245, PubMed:11689480). Increases binding of AHCYL1/IRBIT to ITPR1 (PubMed:27995898). Reduces ITPR1-mediated calcium release from the endoplasmic reti...
Polypeptides: Bcl-2-like protein 10Synonyms: Bcl2-L-10START domain-containing protein 10
go.drugbank.com/bio_entities/BE0021582TransporterHumansMay play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl cha...
Polypeptides: START domain-containing protein 10Synonyms: StAR-related lipid transfer protein 10Potassium alum
go.drugbank.com/drugs/DB09087ApprovedWithdrawnPotassium alum is formed by large, transparent crystals that are used in different products like food or drugs as a buffer, neutralizing or forming agent.[T60] … Potassium alum is considered by the FDA as a generally recognized as safe (GRAS) substance.
Mixtures: Gingibraid W Alum Pot Sulf and Epin 0e, Gingibraid W Epineph and Alum 1eProducts: Gingibraid W Alum Pot Sulf 1a 0.35mg/2.5cm, Gingibraid W Alum Pot Sulf 0a 0.25mg/2.5cmGlycine
go.drugbank.com/drugs/DB00145ApprovedInvestigationalNutraceuticalVet approvedA non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
Mixtures: Primene 10% pur - Infusionslösung, Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose InjecProducts: GLICINA IRRIGACION USP (1.5% W/V)BOLSA POR 3000 ML, GLICINA IRRIGACION AL 1.5%MASTER MEDICALRitodrine
go.drugbank.com/drugs/DB00867ApprovedWithdrawnAdrenergic beta-agonist used to control premature labor.
Synonyms: p-Hydroxy-alpha-(1-((p-hydroxyphenethyl)amino)ethyl)benzyl alcoholProducts: PRE-PAR 50 MG/5 ML IM/IV ÇÖZELTİ İÇEREN AMPUL, 1 AMPULPeramivir
go.drugbank.com/drugs/DB06614ApprovedInvestigationalDue to the poor oral bioavailability, the oral formulation of the drug was previously abandoned by Johnson and Johnson Company. … The development of peramivir has been supported by the US Department of Health and Human Services as part of the government's effort to prepare for a flu pandemic.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseProducts: Influviran 200 mg/20 mL IV İnfüzyonluk Çözelti Hazırlamak İçin Konsantre (10 Adet), Influviran 200 mg/20 mL IV İnfüzyonluk Çözelti Hazırlamak İçin Konsantre (3 Adet)Nicorandil
go.drugbank.com/drugs/DB09220ApprovedInvestigationalWithdrawnIt is often used for patients with angina who remain symptomatic despite optimal treatment with other antianginal drugs [T28]. … It is a niacinamide derivative that induces vasodilation of arterioles and large coronary arteries by activating potassium channels.
Categories: Heterocyclic Compounds, 1-RingInternational brands: Av-Cor, K-CorTofacitinib
go.drugbank.com/drugs/DB08895ApprovedInvestigationalTofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and immune cell function. … It is approved by the FDA for treatment of moderate to severe rheumatoid arthritis that responds inadequately to methotrexate or in those who are intolerant to methotrexate.
Categories: Heterocyclic Compounds, 1-Ring, Biologics for Rheumatoid Arthritis TreatmentProducts: Tositin 10 mg Film Kaplı Tablet, 56 ADET, XELJANZ® XR 11 MG TABLETAS DE LIBERACIÓN MODIFICADA