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Diethylpropion
go.drugbank.com/drugs/DB00937ApprovedIllicitInvestigationalA appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category.
Products: Diethylpropion Hydrochloride ER, Diethylpropion HydrochlorideER ERBortezomib
go.drugbank.com/drugs/DB00188ApprovedInvestigational[L14180] However, multiple mechanisms may be involved in the anticancer activity of bortezomib.[A204083] Bortezomib was first synthesized in 1995. … [A204083] In May 2003, bortezomib became the first anticancer proteasome inhibitor that was approved by the FDA under the trade name VELCADE.
Synonyms: N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamideProducts: BORTEZOMIB EG, MYBORTE 1.0mg (Bortezomib Powder for Solution for Injection 1.0mg/vial)Apremilast
go.drugbank.com/drugs/DB05676ApprovedInvestigational[A181244,L7495] Initially approved in 2014, it is marketed by Celgene. … [L7501] In July 2019, apremilast was granted a new FDA approval for the treatment of oral ulcers associated with Behcet's disease, an autoimmune condition that causes recurrent skin, blood vessel, and
Synonyms: N-{2-[(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamideProducts: Aprezo 10mg Film Coated TabletsMavacamten
go.drugbank.com/drugs/DB14921ApprovedInvestigationalIt received initial US FDA approval in 2022, and it is one of the first myosin inhibitors to be used in humans. … [A248440] Mavacamten was also approved by Health Canada in October 2022 and by EMA in July 2023 for the same indication.[L44106,L47471]
Products: CAMZYOS® 10MG CAPSULAS DURASTazobactam
go.drugbank.com/drugs/DB01606ApprovedInvestigationaland mortality in hospitalized patients. … Piperacillin-tazobactam was initially approved by the FDA in 1994, and ceftolozane-tazobactam was approved by the FDA in 2014[FDA label], providing wider antibacterial coverage for gram-negative infections
Mixtures: PIPERACILINA/TAZOBACTAM 4G/500MG, Zosyn Pharmacy Bulk PackageProducts: TAZOCIN EFMetenolone
go.drugbank.com/drugs/DB13710InvestigationalProducts: RIMOBOLAN 100MG/1 ML ENJEKSIYONLUK COZELTI ICEREN AMPUL, 100 ADET, RIMOBOLAN 100MG/1 ML ENJEKSIYONLUK COZELTI ICEREN AMPUL, 50 ADETErtapenem
go.drugbank.com/drugs/DB00303ApprovedInvestigational[L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002.
Synonyms: (4R,5S,6S)-3-((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acidProducts: Ertapenem AptaPharma 1 g Pulver für ein Konzentrat zur Herstellung einer Infusionslösung, Ertapenem Panpharma 1 g Pulver für ein Konzentrat zur Herstellung einer InfusionslösungTheophylline
go.drugbank.com/drugs/DB00277ApprovedInvestigationalA methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine recep...
Mixtures: Theophylline in Dextrose, Theophylline in DextroseProducts: Theochron Srt 100mg, Theo ERRopinirole
go.drugbank.com/drugs/DB00268ApprovedInvestigationalIn 2005, it was the first drug approved in the US for the management of primary moderate to severe restless legs syndrome [A174547]. … Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease.
Products: REQUIP 1.0MG, ROPINIROLO EGMicafungin
go.drugbank.com/drugs/DB01141ApprovedInvestigationalMicafungin is an antifungal drug. … It belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall.
Products: Micafungin in Sodium Chloride, Micafungin In 0.9% Sodium Chloride Injection