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De Novo Triacylglycerol Biosynthesis TG(16:0/22:4(7Z,10Z,13Z,16Z)/20:0)
smpdb.ca/view/SMP0018047MetabolicThe next three steps are localized to the endoplasmic reticulum membrane. … Second, the mitochondrial outer membrane enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn-glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic
De Novo Triacylglycerol Biosynthesis TG(16:0/22:4(7Z,10Z,13Z,16Z)/22:0)
smpdb.ca/view/SMP0018048MetabolicThe next three steps are localized to the endoplasmic reticulum membrane. … Second, the mitochondrial outer membrane enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn-glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic
De Novo Triacylglycerol Biosynthesis TG(18:0/16:0/22:4(7Z,10Z,13Z,16Z))
smpdb.ca/view/SMP0018302MetabolicThe next three steps are localized to the endoplasmic reticulum membrane. … Second, the mitochondrial outer membrane enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn-glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic
De Novo Triacylglycerol Biosynthesis TG(20:0/16:0/22:4(7Z,10Z,13Z,16Z))
smpdb.ca/view/SMP0018924MetabolicThe next three steps are localized to the endoplasmic reticulum membrane. … Second, the mitochondrial outer membrane enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn-glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic
Phosphatidylethanolamine Biosynthesis PE(16:0/22:6(4Z,7Z,10Z,12E,16Z,19Z)-OH(14))
smpdb.ca/view/SMP0127210MetabolicSecond, choline-phosphate cytidylyltransferase, localized to the endoplasmic reticulum membrane, catalyzes the conversion of phosphocholine to CDP-choline. … They are the second most abundant phospholipid in eukaryotic cell membranes, and contrary to phosphatidylcholine, it is concentrated with phosphatidylserine in the cell membrane's inner leaflet.
Phosphatidylethanolamine Biosynthesis PE(16:0/22:6(4Z,8Z,10Z,13Z,16Z,19Z)-OH(7))
smpdb.ca/view/SMP0127213MetabolicSecond, choline-phosphate cytidylyltransferase, localized to the endoplasmic reticulum membrane, catalyzes the conversion of phosphocholine to CDP-choline. … They are the second most abundant phospholipid in eukaryotic cell membranes, and contrary to phosphatidylcholine, it is concentrated with phosphatidylserine in the cell membrane's inner leaflet.
Cenegermin
go.drugbank.com/drugs/DB13926ApprovedInvestigationalThe prevalence of neurotrophic keratitis has been estimated to be less than five in 10,000 individuals. … The loss of corneal sensation impairs corneal health, causing progressive damage to the top layer of the cornea, including corneal thinning, ulceration, and perforation in severe cases.
Chlormadinone acetate
go.drugbank.com/drugs/DB15903ApprovedWithdrawn[L43942,L42975] Chlormadinone acetate continues to be used in other countries due to its high contraceptive efficacy and tolerability.[A254422,L33974]
Mixtures: BELARA film-coated tablet 0.03mg/2mgDiphenylpyraline
go.drugbank.com/drugs/DB01146ApprovedAntihistamines prevent, but do not reverse, responses mediated by histamine alone. … Antihistamines used in the treatment of allergy act by competing with histamine for H 1-receptor sites on effector cells.
Cardiolipin Biosynthesis CL(16:0/16:0/18:2(9Z,12Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))
smpdb.ca/view/SMP0027013MetabolicPA is then transferred to the inner mitochondrial membrane to continue cardiolipin synthesis. … Second, the mitochondrial outer membrane enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn-glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic