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TSHA-118
go.drugbank.com/drugs/DB16996ExperimentalTSHA-118 is a self-complementary AAV9 gene replacement therapy designed to express a human codon-optimized CLN1 transgene for the treatment of CLN1 disease.
ACT-101
go.drugbank.com/drugs/DB17000ExperimentalACT-101 is a recombinant human alpha-fetoprotein or rhAFP.
Indatraline
go.drugbank.com/drugs/DB17032ExperimentalIndatraline is a nonselective monoamine reuptake inhibitor.[A253022]
Dacinostat
go.drugbank.com/drugs/DB17034ExperimentalDacinostat is a novel histone deacetylase inhibitor.[A253032]
SB 224289
go.drugbank.com/drugs/DB17052ExperimentalSB-224289 is a small molecule with a high affinity for human 5-HT1B receptors.[A253122]
Spiperone
go.drugbank.com/drugs/DB17056ExperimentalSpiperone is a dopamine antagonist that binds dopamine and serotonin receptors.[A253142]
TW-37
go.drugbank.com/drugs/DB17059ExperimentalTW-37 is a small-molecule inhibitor of Bcl-2 investigated for its anti-cancer properties.[A253157]
U-0126
go.drugbank.com/drugs/DB17060ExperimentalU-0126 is a direct inhibitor of the mitogen-activated protein-kinase kinase family members, MEK-1 and MEK-2.[A253162]
ZM-39923
go.drugbank.com/drugs/DB17064ExperimentalZM-39923 is a small molecule that inhibits Janus kinase and human tissue transglutaminase (TGM2).[A253177]
Synonyms: Jak3 inhibitor ivAutologous Hematopoietic Peripheral Blood Stem Cells
go.drugbank.com/drugs/DB17067InvestigationalAutologous hematopoietic peripheral blood stem cells were tested in a clinical trial (NCT00424489) by Northwestern University for the treatment of refractory myasthenia gravis.