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Retifanlimab
go.drugbank.com/drugs/DB15766ApprovedInvestigational[L45603,L45613] The use of retifanlimab in combination with other oncology drugs for the treatment of metastatic gastroesophageal adenocarcinoma has also been evaluated.[A258383,A258388]
Glycochenodeoxycholic Acid
go.drugbank.com/drugs/DB02123ExperimentalA bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed.
Isothipendyl
go.drugbank.com/drugs/DB08802InvestigationalIsothipendyl is an antihistamine and anticholinergic used as an antipruritic.
Eladocagene exuparvovec
go.drugbank.com/drugs/DB16780ApprovedInvestigational[A253687] It was subsequently approved by the FDA in November 2024.[L51898,L51893]
Raseglurant
go.drugbank.com/drugs/DB05070InvestigationalThe orally available small molecule drug candidate, which is highly specific for mGluR5, was discovered at Addex in 2003. It is developed for the treatment of GERD, migraine and anxiety.
Rupintrivir
go.drugbank.com/drugs/DB05102ExperimentalRupintrivir was active against all 48 HRV serotypes tested in a cell protection assay in H1-HeLa cells. It is designed to combat colds caused by rhinovirus.
Colforsin
go.drugbank.com/drugs/DB02587InvestigationalHas antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also lowers intraocular pressure and promotes release of hormones from the pituitary gland
Mosapride
go.drugbank.com/drugs/DB11675InvestigationalMosapride has been investigated for the treatment and diagnostic of Constipation, Type 2 Diabetes, Functional Dyspepsia, Functional Constipation, and Epigastric Pain Syndrome, among others.
Coagulin-B
go.drugbank.com/drugs/DB17703Experimental[A259038, A259043] It was previously investigated for the treatment of hemophilia; however, the manufacturing company discontinued the Phase I trial in 2004, halting its further development and investigation