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Displaying results 7741 - 7750 of 8696 in total
  1. Target

    E3 ubiquitin-protein ligase XIAP

    go.drugbank.com/bio_entities/BE0001156
    TargetHumans

    -linked polyubiquitination of RIPK2 downstream of NOD1 and NOD2, thereby transforming RIPK2 into a scaffolding protein for downstream effectors, ultimately leading to activation of the NF-kappa-B and MAP

    Synonyms: Baculoviral IAP repeat-containing protein 4
  2. Drug

    Ilaprazole

    go.drugbank.com/drugs/DB11964
    Investigational

    Ilaprazole has been investigated in Helicobacter Infections.

    Categories: Drugs for Acid Related Disorders, Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord)
  3. Drug

    Plinabulin

    go.drugbank.com/drugs/DB05992
    Investigational

  4. Drug

    Desmoteplase

    go.drugbank.com/drugs/DB04925
    Investigational

    When a vampire bat bites its victim, it secretes an enzyme that prevents the blood from clotting.

  5. Drug

    VY-HTT01

    go.drugbank.com/drugs/DB16999
    Investigational

    VY-HTT01 is comprised of an adeno-associated virus capsid (AAV1) and a proprietary transgene that harnesses the canonical RNA interference pathway to selectively knock down levels of HTT mRNA.

  6. Drug

    RO7300490

    go.drugbank.com/drugs/DB17535
    Investigational

    RO7300490 is an investigational Fibroblast Activation Protein-α (FAP) targeted CD40 agonist.

  7. Drug

    Pipenzolate

    go.drugbank.com/drugs/DB13844
    Investigational

    Categories: Drugs for Functional Gastrointestinal Disorders
  8. Drug

    Epitestosterone

    go.drugbank.com/drugs/DB07768
    Experimental

    Epitestosterone acts as an antiandrogen in various target tissues. The ratio between testosterone/epitestosterone is used to monitor anabolic drug abuse.

  9. Drug

    Mepiprazole

    go.drugbank.com/drugs/DB09197
    Experimental

    Mepiprazole is marketed in Spain for the treatment of anxiety neuroses. … It acts as a 5-HT2A and α1-adrenergic receptor antagonist, and has also been shown to inhibit the reuptake and induce the release of serotonin, dopamine, and norepinephrine to varying extents.

  10. Drug

    Emricasan

    go.drugbank.com/drugs/DB05408
    Investigational

    Emricasan is the first caspase inhibitor tested in human which has received orphan drug status by FDA. It is developed by Pfizer and made in such a way that it protects liver cells from excessive apoptosis.