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Displaying results 7761 - 7770 of 10000 in total
  1. Drug

    SB 224289

    go.drugbank.com/drugs/DB17052
    Experimental

    SB-224289 is a small molecule with a high affinity for human 5-HT1B receptors.[A253122]

    Salts: SB 224289 hydrochlorideCategories: Heterocyclic Compounds, 1-Ring
  2. Drug

    Spiperone

    go.drugbank.com/drugs/DB17056
    Experimental

    Spiperone is a dopamine antagonist that binds dopamine and serotonin receptors.[A253142]

  3. Drug

    TW-37

    go.drugbank.com/drugs/DB17059
    Experimental

    TW-37 is a small-molecule inhibitor of Bcl-2 investigated for its anti-cancer properties.[A253157]

    Synonyms: Benzamide, n-(4-((2-(1,1-dimethylethyl)phenyl)sulfonyl)phenyl)-2,3,4-trihydroxy-5-((2-(1-methylethyl)phenyl)methyl)-, N-(4-((2-(1,1-dimethylethyl)phenyl)sulfonyl)phenyl)-2,3,4-trihydroxy-5-((2-(1-methylethyl)phenyl)methyl)benzamide
  4. Drug

    U-0126

    go.drugbank.com/drugs/DB17060
    Experimental

    U-0126 is a direct inhibitor of the mitogen-activated protein-kinase kinase family members, MEK-1 and MEK-2.[A253162]

    Salts: U-0126-EtOHSynonyms: 1,4-diamino-2,3-dicyano-1,4-bis(2-aminophenylthio)butadiene, Butanedinitrile, bis(amino((2-aminophenyl)thio)methylene)-, (2z,3z)-
  5. Drug

    ZK-93423

    go.drugbank.com/drugs/DB17063
    Experimental

    ZK-93423 is a beta-carboline with muscle relaxant activity with agonistic properties at the benzodiazepine receptor.[A253172]

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: 9H-Pyrido[3,4-b]indole-3-carboxylicacid, 4-(methoxymethyl)-6-(phenylmethoxy)-, ethyl ester
  6. Drug

    ZM-39923

    go.drugbank.com/drugs/DB17064
    Experimental

    ZM-39923 is a small molecule that inhibits Janus kinase and human tissue transglutaminase (TGM2).[A253177]

    Synonyms: 1-propanone, 3-((1-methylethyl)(phenylmethyl)amino)-1-(2-naphthalenyl)-, 3-(benzyl(propan-2-yl)amino)-1-(naphthalen-2-yl)propan-1-one
  7. Drug

    Autologous Hematopoietic Peripheral Blood Stem Cells

    go.drugbank.com/drugs/DB17067
    Investigational

    Autologous hematopoietic peripheral blood stem cells were tested in a clinical trial (NCT00424489) by Northwestern University for the treatment of refractory myasthenia gravis.

  8. Drug

    αAβ–Gas6

    go.drugbank.com/drugs/DB17069
    Experimental

    It is made of a single chain variable fragment (scFv) of an Amyloid β (Aβ)-targeting monoclonal antibody fused with a truncated receptor binding domain of growth arrest-specific 6 (Gas6), which is a ligand … αAβ–Gas6 is a chimeric fusion protein being investigated in preclinical studies as an immunotherapeutic agent for Alzheimer's disease (AD).

  9. Drug

    Tabelecleucel

    go.drugbank.com/drugs/DB17072
    ApprovedInvestigational

    It is produced by mixing T-cells with B-cells that have been infected with the Epstein-Barr virus (EBV). … Both T-cells and B-cells are obtained from the same donor, and T-cells are grown to increase their numbers.

  10. Drug

    AZD2066

    go.drugbank.com/drugs/DB17078
    Investigational

    Synonyms: Pyridine, 4-(5-((1r)-1-(5-(3-chlorophenyl)-3-isoxazolyl)ethoxy)-4-methyl-4h-1,2,4-triazol-3-yl)-Categories: Heterocyclic Compounds, 1-Ring, Receptor, Metabotropic Glutamate 5, antagonists & inhibitors