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Phenaridine
go.drugbank.com/drugs/DB09178ExperimentalIllicitIt was developed in 1972, and is used for surgical anasthesia in Russia. Phenaridine has similar effects to fentanyl. In rat studies, it was less potent than fentanyl. … Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue
Amdizalisib
go.drugbank.com/drugs/DB21514InvestigationalAmdizalisib is under investigation in clinical trial NCT05713110 (A Study of Tazemetostat in Combination With HMPL-689 in Patients With Relapsed/Refractory Lymphoma).
Fasudil
go.drugbank.com/drugs/DB08162InvestigationalFasudil has been investigated in Carotid Stenosis.
Felezonexor
go.drugbank.com/drugs/DB21067InvestigationalFelezonexor is under investigation in clinical trial NCT02667873 (A Trial of a Novel XPO1 Inhibitor in Participants With Advanced Solid Tumors). … The usage of the INN stem '-nexor' in the name indicates that Felezonexor is a nuclear export inhibitor.
Telenzepine
go.drugbank.com/drugs/DB19508InvestigationalTelenzepine is under investigation in clinical trial NCT01155531 (Safety & Tolerability of a Combination of Antidepressant and Peptic Ulcer Drug in Overweight Healthy Subjects). … The usage of the INN stem '-zepine' in the name indicates that Telenzepine is a tricyclic compound.
Setileuton
go.drugbank.com/drugs/DB19550InvestigationalSetileuton is under investigation in clinical trial NCT00404313 (The Effect of MK0633 in Patients With Chronic Asthma (0633-007)). Setileuton has a monoisotopic molecular weight of 463.12 Da. … The usage of the INN stem '-leuton' in the name indicates that Setileuton is a 5-lipo-oxygenase inhibitor, anti-inflammatory.
Icovamenib
go.drugbank.com/drugs/DB21669InvestigationalIcovamenib is under investigation in clinical trial NCT06152042 (Phase 2 Trial of BMF-219 in Participants With Type 1 Diabetes Mellitus). Icovamenib has a monoisotopic molecular weight of 566.28 Da. … The usage of the INN stem '-menib' in the name indicates that Icovamenib is a menin interaction inhibitor.
Maropitant
go.drugbank.com/drugs/DB11427ExperimentalVet approvedIt was approved by the FDA in 2007 for use in dogs, and more recently has also been approved for use in cats. … Maropitant, used as maropitant citrate, is a neurokinin receptor antagonist, which was developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs.