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Cation-dependent mannose-6-phosphate receptor
go.drugbank.com/bio_entities/BE0004494TargetTransporterHumansLysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal
Polypeptides: Cation-dependent mannose-6-phosphate receptorSynonyms: CD Man-6-P receptor, 46 kDa mannose 6-phosphate receptorTenecteplase
go.drugbank.com/drugs/DB00031ApprovedInvestigationalTenecteplase is a tissue plasminogen activator (tPA) developed from modifications of natural human tPA complementary DNA (cDNA). It is a 527 amino acid with a substitution of threonine 103 with asparagine and substitution of asparagine 1...
Products: METALYSE FOR INJECTION 10,000 u/vialPA3-17
go.drugbank.com/drugs/DB18569InvestigationalPA3-17 is CD7-directed chimeric antigen receptor (CAR) T-cell therapy.
Synonyms: Chimeric Antigen Receptor T Cells targeting CD7Cromoglicic acid
go.drugbank.com/drugs/DB01003ApprovedInvestigationalIt is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.
Categories: Drugs for Obstructive Airway Diseases, Agents for Dermatitis, Excluding CorticosteroidsProducts: CROMO-MACSevelamer
go.drugbank.com/drugs/DB00658ApprovedInvestigationalSevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Categories: Drugs for Treatment of Hyperkalemia and HyperphosphatemiaProducts: Sevelamer Carbonate for Oral Suspension, Sevelamer Carbonate For Oral SuspensionPyridoxine
go.drugbank.com/drugs/DB00165ApprovedInvestigationalNutraceuticalVet approvedAs its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body. … Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods.
Mixtures: For Men, Prenate MaxCategories: Antiinfectives for Systemic Use, Drugs for Treatment of TuberculosisAnastrozole
go.drugbank.com/drugs/DB01217ApprovedInvestigational[A186877,A186955] Anastrozole was first approved for use in the United States in 1995.[L8863] … including anastrozole, have become endocrine drugs of choice in the treatment of postmenopausal breast cancer due to a more favourable efficacy and adverse effect profile as compared to earlier estrogen receptor
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: Mar-anastrozole, Van-anastrozoleTolevamer
go.drugbank.com/drugs/DB01344ApprovedIt may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. … It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among others, HIV.
Categories: Drugs for Treatment of Hyperkalemia and HyperphosphatemiaProducts: <p>KALQUEST® Powder for Oral Suspension 5g/sachet</p>, PMS-SODIUM POLYSTYRENE SULFONATE POWDER FOR SUSPENSION 94.3 mg/gInterferon alfa-2a
go.drugbank.com/drugs/DB00034ApprovedInvestigationalWithdrawnIt is used extensively as an antiviral or antineoplastic agent. An oral form is being developed by Amarillo Biosciences.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsProducts: ROFERON-A PREFILLED SYRINGE FOR INJECTION 3 miu/0.5 mlNicotine
go.drugbank.com/drugs/DB00184ApprovedInvestigationalNicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of it...
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Cytochrome P-450 SubstratesProducts: NICORETTE TRANSDERMAL PATCH 5 mg/16 hr, NICORETTE TRANSDERMAL PATCH 10 mg/16 hr