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Trimethoprim
go.drugbank.com/drugs/DB00440ApprovedInvestigationalVet approvedprevents the synthesis of bacterial DNA and ultimately continued bacterial survival. … Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it
Mixtures: Bactrim DS, Bactrim DSBacitracin
go.drugbank.com/drugs/DB00626ApprovedInvestigationalVet approvedBacitracin is a combination of at least 9 bacitracins.[A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A. … [A181952] The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy.
Mixtures: Dr Bells Pomade, Pomada De La Campana Triple Antibiotic Pain ReliefSynonyms: Bacitracin AMidazolam
go.drugbank.com/drugs/DB00683ApprovedIllicitInvestigational[F2977] This drug was initially approved by the US FDA in 1985, and has been approved for various indications since. … [L45098] In late 2018, the intramuscular preparation was approved by the FDA for the treatment of status epilepticus in adults.
Products: N/aInositol
go.drugbank.com/drugs/DB13178ApprovedInvestigationalWithdrawnIt is considered a pseudovitamin as it is a molecule that does not qualify to be an essential vitamin because even though its presence is vital in the body, a deficiency in this molecule does not translate … [L1113] By the FDA, inositol is considered in the list of specific substances affirmed as generally recognized as safe (GRAS).[L2561]
Mixtures: One A Day Tab, Extra Once A DayCategories: Vitamin B ComplexRopinirole
go.drugbank.com/drugs/DB00268ApprovedInvestigationalRopinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease. … Ropinirole, also known as _ReQuip_, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], [A174547].
Products: ROPINIROL 1A PHARMA 1MG, ROPINIROL 1A PHARMA 2MGEntacapone
go.drugbank.com/drugs/DB00494ApprovedInvestigationalWhen administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased and more sustained plasma levodopa concentrations are reached as compared to the administration … of levodopa and a decarboxylase inhibitor.
Mixtures: LCE 1A PHARMA 100/25/200, LCE 1A PHARMA 100/25/200Mifamurtide
go.drugbank.com/drugs/DB13615ApprovedInvestigationalAs a liposomal formulation, mifamurtide demonstrates an enhanced tumoricidal effect and improved safety profile [A31745]. Mifamurtide is marketed in Europe as Mepact for intravenous infusion. … Also called L-MTP-PE, mifamurtide may be a liposomal form of of the active ingredient MTP-PE, which is a synthetic, less pyrogenic, and longer-acting derivative of muramyl dipeptide (MDP).
Glimepiride
go.drugbank.com/drugs/DB00222ApprovedInvestigationalCompared to [glipizide], another second SU drug, glimepiride has a longer duration of action. … [A177703] Compared to other SUs, glimepiride was associated with a lower risk of developing hypoglycemia and weight gain in clinical trials [A177709] as well as fewer cardiovascular effects than other
Mixtures: GLIMETAL-DP, METGLITAL LEX 850/4 MG TABLETAS DE LIBERACIÓN PROLONGADAProducts: GLIMEPIRID 1A PHARMA 1MG, GLIMEPIRID 1A PHARMA 2MGMepyramine
go.drugbank.com/drugs/DB06691ApprovedVet approvedIt is a first generation antihistamine. However, it rapidly permeates the brain and so often causes drowsiness as a side effect.
Mixtures: Zotex-D, Deconsal DMOmbitasvir
go.drugbank.com/drugs/DB09296ApprovedInvestigationalOmbitasvir is an inhibitor of NS5A, a protein essential for viral replication and virion assembly [FDA Label]. … Ombutasvir is also available as a fixed-dose combination product with [DB09297] and [DB00503] as the FDA- and Health Canada-approved product Technivie.