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MIP-1095 I-131
go.drugbank.com/drugs/DB14978InvestigationalMIP-1095 I-131 is under investigation in clinical trial NCT03030885 (Use of an Experimental Radiopharmaceutical (131I-MIP-1095) in Men With Metastatic Castration-Resistant Prostate Cancer (mCRPC)).
177Lu-PSMA-I&T
go.drugbank.com/drugs/DB22176Investigational177Lu-PSMA-I&T is under investigation in clinical trial NCT04886986 (Phase I/II 225Ac-J591 Plus 177Lu-PSMA-I&T for Progressive Metastatic Castration Resistant Prostate Cancer).
Synonyms: 177Lu-PSMA I&T, 177Lu-PSMA-I&TSulbutiamine
go.drugbank.com/drugs/DB13416InvestigationalThe chronic administration of the drug has demonstrated to improve long term memory formation in mice. … It is highly lipophilic, allowing it to cross the blood-brain barrier more easily than other thiamine derivatives.
Necuparanib
go.drugbank.com/drugs/DB16251InvestigationalNecuparanib is under investigation in clinical trial NCT01621243 (M402 in Combination With Nab-paclitaxel and Gemcitabine in Pancreatic Cancer).
ABX-196
go.drugbank.com/drugs/DB16339InvestigationalABX-196 is under investigation in clinical trial NCT03897543 (ABX196 in Combination With Nivolumab in Patients With Hepatocellular Carcinoma).
Deferitazole
go.drugbank.com/drugs/DB13120InvestigationalIt has been used in trials studying the treatment and basic science of Beta-thalassemia, Hepatic Impairment, Impaired Renal Function, Transfusional Iron Overload, and Iron Overload Due to Repeated Red … Deferitazole is an iron chelator.
Zeteletinib
go.drugbank.com/drugs/DB21491InvestigationalZeteletinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Zeteletinib is a tyrosine kinase inhibitor. … Zeteletinib is under investigation in clinical trial NCT03780517 (Safety, Efficacy, and Tolerability of BOS172738 in Patients With Advanced Rearranged During Transfection (RET) Gene-Altered Tumors).
Xeruborbactam
go.drugbank.com/drugs/DB21512InvestigationalXeruborbactam is a small molecule drug. The usage of the INN stem '-bactam' in the name indicates that Xeruborbactam is a ẞ-lactamase inhibitor. … Xeruborbactam is under investigation in clinical trial NCT07104162 (A Study to Investigate Safety and Pharmacokinetics of Intravenous Cefiderocol/Xeruborbactam in Participants With Renal Impairment).
Gridegalutamide
go.drugbank.com/drugs/DB21593InvestigationalGridegalutamide is a small molecule drug. The usage of the INN stem '-lutamide' in the name indicates that Gridegalutamide is a non-steroid antiandrogen. … Gridegalutamide is under investigation in clinical trial NCT04428788 (Study to Evaluate the Safety and Tolerability of CC-94676 in Participants With Metastatic Castration-Resistant Prostate Cancer).
Docirbrutinib
go.drugbank.com/drugs/DB21606InvestigationalDocirbrutinib is under investigation in clinical trial NCT05602363 (AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma). … Docirbrutinib is a small molecule drug. The usage of the INN stem '-brutinib' in the name indicates that Docirbrutinib is a agammaglobulinaemia tyrosine kinase (Bruton tyrosine kinase) inhibitor.