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Displaying results 7981 - 7990 of 10000 in total
  1. Drug

    CAM-101

    go.drugbank.com/drugs/DB18414
    Investigational

    CAM-101 is an allogeneic human platelet lysate product depleted of fibrinogen.

  2. Drug

    TTX-siPDL1

    go.drugbank.com/drugs/DB18550
    Experimental

    TTX-siPDL1 is an siRNA-based modulator of programmed death-ligand 1.

  3. Drug

    TPMPA

    go.drugbank.com/drugs/DB16754
    Experimental

    TPMPA ((1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid) is a selective antagonist of GABA<sub>C</sub> receptors (also known as GABA-ρ or GABA<sub>A-ρ</sub> receptors). … [A245308,A245313] TPMPA is used as a pharmacological probe for the investigation of GABA<sub>C</sub> receptor function.[A245313]

  4. Drug

    Rimiducid

    go.drugbank.com/drugs/DB04974
    Investigational

    Rimiducid is a lipid-permeable tacrolimus analogue and a protein dimerizer. … It was designed to overcome limitations of current cellular immunotherapies used for cancer and other blood disorders by enhancing the control of the immune cell activity and function.

  5. Drug

    R-95845

    go.drugbank.com/drugs/DB07327
    Experimental

    R-95845 is an inhibitor of HIV-1 reverse transcriptase.

  6. Drug

    LY-2183240

    go.drugbank.com/drugs/DB17035
    Experimental

    LY-2183240 is an inhibitor of endocannabinoid reuptake/breakdown.[A253037]

  7. Drug

    Talizumab

    go.drugbank.com/drugs/DB05797
    Experimental

    TNX-901 is a therapeutic monoclonal antibodies designed to address significant unmet medical needs in the areas of asthma, allergy, inflammation and other diseases affecting the human immune system.

  8. Drug

    Bexotegrast

    go.drugbank.com/drugs/DB16515
    Investigational

    development of this compound[L31708]. … PLN-74809 is a small-molecule that dually inhibits both α<sub>v</sub>β<sub>6</sub> and α<sub>v</sub>β<sub>1</sub> to treat both idiopathic pulmonary fibrosis (IPF) and primary sclerosing cholangitis (PSC

  9. Drug

    CR002

    go.drugbank.com/drugs/DB05139
    Investigational

    CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived growth factor-D (PDGF-D), a target shown to play a role in kidney inflammation. … This is a novel therapeutic approach to treat kidney inflammation.

    Synonyms: Human monoclonal antibody against platelet-derived growth factor D
  10. Drug

    MLN-977

    go.drugbank.com/drugs/DB05431
    Experimental

    MLN-977 is a small molecule compound that inhibits the production of leukotrienes, especially 5-lipoxygenase. It is developed by PharmaEngine to treat asthma and chronic obstructive pulmonary disease.