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Olopatadine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175035Drug actionOlopatadine is a histamine H1 antagonist used to treat allergic conjunctivitis and rhinitis. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in or...
Azelastine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175036Drug actionAzelastine is a histamine H1-receptor antagonist used intranasally to treat allergic and vasomotor rhinitis and in an ophthalmic solution to treat allergic conjunctivitis. H1-antihistamines interfere with the agonist action of histamine ...
Chlorpheniramine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175042Drug actionChlorpheniramine is a histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are admi...
Esmirtazapine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175044Drug actionEsmirtazapine is an H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as allergic rhinitis, alle...
Dimetotiazine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175045Drug actionDimetotiazine is an H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as allergic rhinitis, alle...
Dexchlorpheniramine maleate H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175046Drug actionDexchlorpheniramine maleate is a first generation H1-antihistamine used to treat allergic and vasomotor rhinitis, allergic conjunctivitis, and mild urticaria and angioedema. H1-antihistamines interfere with the agonist action of histamin...
Zuclopenthixol H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175061Drug actionZuclopenthixol is a weak H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as allergic rhinitis,...
Aripiprazole lauroxil H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175069Drug actionAripiprazole lauroxil is a long-acting injectable atypical antipsychotic drug used in the treatment of schizophrenia in adult patients. It is a prodrug of aripiprazole, which acts as a partial agonist at the D2 and 5-HT1A receptors, and ...
VEGF Signaling
smpdb.ca/view/SMP0524112SignalingVascular Endothelial Growth Factor (VEGF) is a critical protein that promotes angiogenesis, vascular permeability, and endothelial cell function. VEGF binds to VEGF receptor 2 (VEGFR2) on endothelial cells, triggering a signaling cascade...
Sphingolipid Signaling (Receptor)
smpdb.ca/view/SMP0524344SignalingSphingosine‑1‑phosphate (S1P) is a potent bioactive lipid mediator synthesized intracellularly by the phosphorylation of sphingosine by sphingosine kinases SphK1 and SphK2 at the plasma membrane and is then exported via spinster 2 (SPNS2...