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Lactulose
go.drugbank.com/drugs/DB00581ApprovedInvestigationaland its first clinical use for treating PSE was not until 1966. … [FDA Label,L6199,L6202] Despite being first synthesized in 1929[A178081], investigations regarding its possible use as a laxative for the treatment of chronic constipation did not occur until the 1960s
Products: Lactulose Solution USP, Lactulose Solution, USP 667mg/mlSelenious acid
go.drugbank.com/drugs/DB11127ApprovedSelenious acid is the acid form of sodium selenite, a form of selenium . Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation. It also plays an important role in maintaining the general hea...
Products: Selepen Inj 40mcg/ml USP, Selenious Acid Injection, USPZidovudine
go.drugbank.com/drugs/DB00495ApprovedInvestigationalA dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseProducts: Zidovudine Oral Solution USP, ZIDOVEX 300 (Zidovudine Tablets USP 300mg)Niacin
go.drugbank.com/drugs/DB00627ApprovedInvestigationalNutraceuticalNiacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.
Products: Niacin Tab 100mg USP, Niacin Tablets 500mg USPLevothyroxine
go.drugbank.com/drugs/DB00451ApprovedInvestigationalHowever, this is no longer recommended for the majority of patients due to several clinical concerns including limited controlled trials supporting its use. … [F4633] T<sub>4</sub> and T<sub>3</sub> act on nearly every cell of the body, but have a particularly strong effect on the cardiac system.
Products: Synthroid Tab 88mcg USP, Synthroid Tab 75mcg USPAbiraterone
go.drugbank.com/drugs/DB05812ApprovedInvestigational[A3811, A260880, L40968] Abiraterone was first approved by the FDA and EMA on April,[A260880] July,[L47745] and September 2011,[A260880] respectively. … [L54773,L54768] As abiraterone has poor oral bioavailability and is susceptible to hydrolysis by esterases, abiraterone acetate was developed as an orally bioavailable prodrug with enhanced stability
Products: ABIRANAT TABLETS 250MG USP, ONCOPROS - ABIRATERONE ACETATE TABLETS USP 250MGPolymyxin B
go.drugbank.com/drugs/DB00781ApprovedInvestigationalVet approvedPolymyxin B has a narrow therapeutic index and so its use is limited and unlikely to be used first line[A176429]. … Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic[A176426,FDA Label].
Mixtures: Polyderm Ointment USP, Antibiotic Ointment USPCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseRopivacaine
go.drugbank.com/drugs/DB00296ApprovedInvestigationalRopivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin.
Products: Ropivacaine Hydrochloride Injection USP, Ropivacaine Hydrochloride Injection, USPDiphenhydramine
go.drugbank.com/drugs/DB01075ApprovedInvestigationalmedications that have been marketed for "night time" use [L5263, L5281, L5287]. … While its use in allergy therapy can sometimes fall out of favor due to its sedative effect, diphenhydramine has been repurposed for use within many non-prescription over-the-counter sleep aids and cough-and-cold
Mixtures: Benadryl Bug Bite Relief, Children's Benadryl Bug Bite ReliefCategories: Antihistamines for Topical Use, Antihistamines for Systemic UseBretylium
go.drugbank.com/drugs/DB01158ApprovedRecent evidence has shown that bretylium may also inhibit the Na,K-ATPase by binding to the extracellular K-site.
Products: Bretylium Tosylate Injection USP