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Displaying results 71 - 80 of 10000 in total
  1. Drug

    Nemvaleukin alfa

    go.drugbank.com/drugs/DB18187
    Investigational

    Synonyms: Cys125>Ser51), fused via peptidyl linker (60GG61) to human interleukin 2 fragment (62-132), fused via peptidyl linker (133GSGGGS138) to human interleukin 2 receptor α-chain fragment (139-303), produced in, Fusion protein comprised of a circularly-permuted interleukin-2 (IL-2) with the extracellular domain of IL-2 receptor alpha
  2. Pathway

    Indium In-111 oxyquinoline Drug Metabolism

    smpdb.ca/view/SMP0130676
    Metabolic

    Indium In-111 oxyquinoline passes through the liver and is then excreted from the body mainly through the kidney. … Indium In-111 oxyquinoline is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.

    Drugs: Indium In-111 oxyquinoline
  3. Drug

    Erythropoietin

    go.drugbank.com/drugs/DB00016
    ApprovedInvestigational

    Epoetin alfa (Epoge) was developed by Amgen Inc. in 1983 as the first rhEPO commercialized in the United States, followed by other alfa and beta formulations. … Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells.

    Products: AIMAPEX 4000 IU/ML IN PREFILLED SYRINGE, HEMA-PLUS 1000 IU IN 0.25 ML PREFILLED SYRINGE
  4. Drug

    Magnesium sulfate

    go.drugbank.com/drugs/DB00653
    ApprovedInvestigationalVet approved

    A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. … It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions.

    Synonyms: magnesium(II) sulfateMixtures: Magnesium Sulfate In 5% Dextrose Inj(20mg/ml), Multiple Electrolyte Additive Inj
  5. Drug

    Insulin human

    go.drugbank.com/drugs/DB00030
    ApprovedInvestigational

    Insulin is an important treatment in the management of Type 1 Diabetes (T1D) which is caused by an autoimmune reaction that destroys the beta cells of the pancreas, resulting in the body not being able … While still available in the US, Afrezza has had similar concerns associated with its use, and had an FDA "black box" warning added to it to warn about use in patients with chronic lung disease.

    Mixtures: Humulin 10/90 Inj, Humulin 10/90 InjCategories: Drugs Used in Diabetes
  6. Drug

    Methotrexate

    go.drugbank.com/drugs/DB00563
    ApprovedInvestigational

    [A180322,L7144,L7147,L7150,L7180] Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and severe psoriasis only if first line treatment has failed or patients … [A180322] Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and non-Hodgkin's lymphoma

    Synonyms: 4-amino-N(10)-methylpteroylglutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acidProducts: INJ METHOTREXATE CS 50MG IN 2ML, INJ METHOTREXATE CS 1000MG IN 10ML
  7. Pathway

    Fatty Acid Elongation in Mitochondria

    smpdb.ca/view/SMP0000054
    Metabolic

    In liver and kidney fatty acid elongation operates best in the presence of both NADH and NADPH, whereas in heart and skeletal muscle, only NADH is required. … Mitochondrial elongation may result in fatty acids up to C16 in length. Fatty acid elongation in mitochondria is essentially the reverse of beta-oxidation for fatty acid oxidation.

    Drugs: NADH · Palmitic Acid
  8. Pathway

    Indium In-111 pentetate Drug Metabolism

    smpdb.ca/view/SMP0130595
    Metabolic

    Indium In-111 pentetate passes through the liver and is then excreted from the body mainly through the kidney. … Indium In-111 pentetate is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.

    Drugs: Indium In-111 pentetate
  9. Drug

    Rabies immune globulin, human

    go.drugbank.com/drugs/DB11603
    Approved

    IMOGAM Rabies Pasteurized should be administered promptly after exposure, in conjunction with rabies vaccine. … IMOGAM Rabies Pasteurized is indicated for post-exposure prophylaxis in persons suspected of exposure to rabies, who have not previously received a complete immunization regimen with a cell culture produced

    Products: Rabipur Pulver und Lösungsmittel zur Herstellung einer Injektionslösung in einer Fertigspritze, EQUIRAB 1000 IU/5ML IM/SC ÇÖZELTI IÇEREN FLAKON, 1 ADET
  10. Drug

    Atropine

    go.drugbank.com/drugs/DB00572
    ApprovedInvestigationalVet approved

    Oral atropine is only available in combination products. … [A251660] Atropine is a relatively inexpensive drug and is included in the World Health Organization List of Essential Medicines.[A251675]

    Products: Atropin Accord 0,1 mg/ml Injektionslösung in einer Fertigspritze, Atropinsulfat Aguettant 0,1 mg/ml Injektionslösung in Fertigspritze